HIV AIDS CT: Difference between revisions
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{{AIDS}} | {{AIDS}} | ||
{{CMG}} '''Associate Editors-in-Chief:''' [[User:Ujjwal Rastogi|Ujjwal Rastogi, MBBS] | {{CMG}}; '''Associate Editors-in-Chief:''' [[User:Ujjwal Rastogi|Ujjwal Rastogi, MBBS]] | ||
==Overview== | ==Overview== | ||
CT scans of chest are important part of diagnosis in HIV patients having pulmonary symptoms. It has an advantage over X-Ray in being more sensitive in detection of early [[interstitial lung disease]], [[lymphadenopathy]], and [[nodules]]. | CT scans of chest are important part of diagnosis in HIV patients having [[pulmonary]] symptoms. It has an advantage over X-Ray in being more sensitive in detection of early [[interstitial lung disease]], [[lymphadenopathy]], and [[nodules]]. | ||
==CT | ==CT== | ||
In HIV patients, nodules can result from bacterial infection (pneumonia or mycobacterial disease) or malignancy (most common being lymphoma). Nodules can be with or without cavitation. CT-guided transthoracic needle biopsy is used to make a definitive diagnosis. | In HIV patients, nodules can result from bacterial infection ([[pneumonia]] or mycobacterial disease) or [[malignancy]] (most common being [[lymphoma]]). Nodules can be with or without cavitation. CT-guided transthoracic needle [[biopsy]] is used to make a definitive diagnosis. | ||
A prospective study done in 30 patients comparing the accuracy of high | A prospective study done in 30 patients comparing the accuracy of [[high resolution CT]] in distinguishing between [[Pneumocystis carinii pneumonia]] and non- Pneumocystis carinii pneumonia in AIDS patients stated that the [[sensitivity]], [[specificity]], [[positive predictive value|positive predictive]] and, [[negative predictive value]]s of the HRCT for the diagnosis for PCP were 100, 83.3, 90.5 and 100 percent, respectively.<ref name="pmid12695843">{{cite journal |author=Hidalgo A, Falcó V, Mauleón S, Andreu J, Crespo M, Ribera E, Pahissa A, Cáceres J |title=Accuracy of high-resolution CT in distinguishing between Pneumocystis carinii pneumonia and non- Pneumocystis carinii pneumonia in AIDS patients |journal=Eur Radiol |volume=13 |issue=5 |pages=1179–84 |year=2003 |month=May |pmid=12695843 |doi=10.1007/s00330-002-1641-6 |url=http://dx.doi.org/10.1007/s00330-002-1641-6 |accessdate=2012-02-12}}</ref> | ||
HRCT fndings, that are '''suggestive of PCP''' are : | HRCT fndings, that are '''suggestive of PCP''' are : | ||
* Diffuse or [[Ground glass opacification on CT|ground glass]] pattern predominately in the upper lobes with or without | * Diffuse or [[Ground glass opacification on CT|ground glass]] pattern predominately in the upper lobes with or without [[cyst]]ic change. | ||
HRCT fndings, that are '''not suggestive of PCP''' are : | HRCT fndings, that are '''not suggestive of PCP''' are : | ||
*"Tree in bud" appearance. | *"Tree in bud" appearance. |
Revision as of 19:34, 18 December 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-in-Chief: Ujjwal Rastogi, MBBS
Overview
CT scans of chest are important part of diagnosis in HIV patients having pulmonary symptoms. It has an advantage over X-Ray in being more sensitive in detection of early interstitial lung disease, lymphadenopathy, and nodules.
CT
In HIV patients, nodules can result from bacterial infection (pneumonia or mycobacterial disease) or malignancy (most common being lymphoma). Nodules can be with or without cavitation. CT-guided transthoracic needle biopsy is used to make a definitive diagnosis.
A prospective study done in 30 patients comparing the accuracy of high resolution CT in distinguishing between Pneumocystis carinii pneumonia and non- Pneumocystis carinii pneumonia in AIDS patients stated that the sensitivity, specificity, positive predictive and, negative predictive values of the HRCT for the diagnosis for PCP were 100, 83.3, 90.5 and 100 percent, respectively.[1]
HRCT fndings, that are suggestive of PCP are :
- Diffuse or ground glass pattern predominately in the upper lobes with or without cystic change.
HRCT fndings, that are not suggestive of PCP are :
- "Tree in bud" appearance.
- Consolidation.
- Bronchiectasis.
- Lymphadenopathy.
References
- ↑ Hidalgo A, Falcó V, Mauleón S, Andreu J, Crespo M, Ribera E, Pahissa A, Cáceres J (2003). "Accuracy of high-resolution CT in distinguishing between Pneumocystis carinii pneumonia and non- Pneumocystis carinii pneumonia in AIDS patients". Eur Radiol. 13 (5): 1179–84. doi:10.1007/s00330-002-1641-6. PMID 12695843. Retrieved 2012-02-12. Unknown parameter
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