Japanese encephalitis causes: Difference between revisions
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==Overview== | |||
The causative agent Japanese encephalitis virus is an enveloped virus of the genus flavivirus; it is closely related to the [[West Nile virus]] and [[St. Louis encephalitis]] virus. Positive sense single stranded RNA genome is packaged in the capsid, formed by the capsid protein. The outer envelope is formed by envelope (E) protein and is the protective antigen. It aids in entry of the virus to the inside of the cell. The genome also encodes several nonstructural proteins also (NS1,NS2a,NS2b,NS3,N4a,NS4b,NS5). NS1 is produced as secretory form also. NS3 is a putative helicase, and NS5 is the viral polymerase. It has been noted that the Japanese encephalitis virus (JEV) infects the [[lumen]] of the [[endoplasmic reticulum]] (ER) and rapidly accumulates substantial amounts of viral proteins for the JEV. | |||
==References== | ==References== |
Revision as of 15:09, 27 December 2012
Japanese encephalitis Microchapters |
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Japanese encephalitis causes On the Web |
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Risk calculators and risk factors for Japanese encephalitis causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
The causative agent Japanese encephalitis virus is an enveloped virus of the genus flavivirus; it is closely related to the West Nile virus and St. Louis encephalitis virus. Positive sense single stranded RNA genome is packaged in the capsid, formed by the capsid protein. The outer envelope is formed by envelope (E) protein and is the protective antigen. It aids in entry of the virus to the inside of the cell. The genome also encodes several nonstructural proteins also (NS1,NS2a,NS2b,NS3,N4a,NS4b,NS5). NS1 is produced as secretory form also. NS3 is a putative helicase, and NS5 is the viral polymerase. It has been noted that the Japanese encephalitis virus (JEV) infects the lumen of the endoplasmic reticulum (ER) and rapidly accumulates substantial amounts of viral proteins for the JEV.