Brugada syndrome electrophysiologic studies: Difference between revisions
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==Overview== | ==Overview== | ||
Patients who are inducible at the time electrophysiologic study have an eightfold increased risk of aborted [[sudden cardiac death]] compared with those patients who are not inducible.<ref> <div>'' Brugada J, Brugada R, Brugada P. Determinants of sudden cardiac death in individuals with the electrocardiographic pattern of Brugada syndrome and no previous cardiac arrest. Circulation''. '' 2003; 108: 3092–3096.''</div></ref> Some groups have advocated that programmed electrical stimulation (PES) be performed to induce [[ventricular fibrillation]] for risk assessment in Brugada patients <ref name="pmid11772879">{{cite journal |author=Brugada J, Brugada R, Antzelevitch C, Towbin J, Nademanee K, Brugada P |title=Long-term follow-up of individuals with the electrocardiographic pattern of right bundle-branch block and ST-segment elevation in precordial leads V1 to V3 |journal=[[Circulation]] |volume=105 |issue=1 |pages=73–8 |year=2002 |month=January |pmid=11772879 |doi= |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=11772879 |issn= |accessdate=2012-10-13}}</ref><ref name="pmid12776858">{{cite journal |author=Brugada P, Brugada R, Mont L, Rivero M, Geelen P, Brugada J |title=Natural history of Brugada syndrome: the prognostic value of programmed electrical stimulation of the heart |journal=[[Journal of Cardiovascular Electrophysiology]] |volume=14 |issue=5 |pages=455–7 |year=2003 |month=May |pmid=12776858 |doi= |url=http://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1045-3873&date=2003&volume=14&issue=5&spage=455 |issn= |accessdate=2012-10-13}}</ref> Other groups have not reproduced the predictive value of these tests,<ref name="pmid11901046">{{cite journal |author=Priori SG, Napolitano C, Gasparini M, Pappone C, Della Bella P, Giordano U, Bloise R, Giustetto C, De Nardis R, Grillo M, Ronchetti E, Faggiano G, Nastoli J |title=Natural history of Brugada syndrome: insights for risk stratification and management |journal=[[Circulation]] |volume=105 |issue=11 |pages=1342–7 |year=2002 |month=March |pmid=11901046 |doi= |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=11901046 |issn= |accessdate=2012-10-13}}</ref><ref name="pmid15642768">{{cite journal |author=Eckardt L, Probst V, Smits JP, Bahr ES, Wolpert C, Schimpf R, Wichter T, Boisseau P, Heinecke A, Breithardt G, Borggrefe M, LeMarec H, Böcker D, Wilde AA |title=Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndrome |journal=[[Circulation]] |volume=111 |issue=3 |pages=257–63 |year=2005 |month=January |pmid=15642768 |doi=10.1161/01.CIR.0000153267.21278.8D |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=15642768 |issn= |accessdate=2012-10-13}}</ref> so the value of programmed electrical stimulation (PES) and inducibility remains controversial. | Patients who are inducible at the time electrophysiologic study have an eightfold increased risk of aborted [[sudden cardiac death]] compared with those patients who are not inducible.<ref> <div>'' Brugada J, Brugada R, Brugada P. Determinants of sudden cardiac death in individuals with the electrocardiographic pattern of Brugada syndrome and no previous cardiac arrest. Circulation''. '' 2003; 108: 3092–3096.''</div></ref> Some groups have advocated that programmed electrical stimulation (PES) be performed to induce [[ventricular fibrillation]] for risk assessment in Brugada patients <ref name="pmid11772879">{{cite journal |author=Brugada J, Brugada R, Antzelevitch C, Towbin J, Nademanee K, Brugada P |title=Long-term follow-up of individuals with the electrocardiographic pattern of right bundle-branch block and ST-segment elevation in precordial leads V1 to V3 |journal=[[Circulation]] |volume=105 |issue=1 |pages=73–8 |year=2002 |month=January |pmid=11772879 |doi= |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=11772879 |issn= |accessdate=2012-10-13}}</ref><ref name="pmid12776858">{{cite journal |author=Brugada P, Brugada R, Mont L, Rivero M, Geelen P, Brugada J |title=Natural history of Brugada syndrome: the prognostic value of programmed electrical stimulation of the heart |journal=[[Journal of Cardiovascular Electrophysiology]] |volume=14 |issue=5 |pages=455–7 |year=2003 |month=May |pmid=12776858 |doi= |url=http://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1045-3873&date=2003&volume=14&issue=5&spage=455 |issn= |accessdate=2012-10-13}}</ref> Other groups have not reproduced the predictive value of these tests,<ref name="pmid11901046">{{cite journal |author=Priori SG, Napolitano C, Gasparini M, Pappone C, Della Bella P, Giordano U, Bloise R, Giustetto C, De Nardis R, Grillo M, Ronchetti E, Faggiano G, Nastoli J |title=Natural history of Brugada syndrome: insights for risk stratification and management |journal=[[Circulation]] |volume=105 |issue=11 |pages=1342–7 |year=2002 |month=March |pmid=11901046 |doi= |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=11901046 |issn= |accessdate=2012-10-13}}</ref><ref name="pmid15642768">{{cite journal |author=Eckardt L, Probst V, Smits JP, Bahr ES, Wolpert C, Schimpf R, Wichter T, Boisseau P, Heinecke A, Breithardt G, Borggrefe M, LeMarec H, Böcker D, Wilde AA |title=Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndrome |journal=[[Circulation]] |volume=111 |issue=3 |pages=257–63 |year=2005 |month=January |pmid=15642768 |doi=10.1161/01.CIR.0000153267.21278.8D |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=15642768 |issn= |accessdate=2012-10-13}}</ref> so the value of programmed electrical stimulation (PES) and inducibility remains controversial. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Patients who are inducible at the time electrophysiologic study have an eightfold increased risk of aborted sudden cardiac death compared with those patients who are not inducible.[1] Some groups have advocated that programmed electrical stimulation (PES) be performed to induce ventricular fibrillation for risk assessment in Brugada patients [2][3] Other groups have not reproduced the predictive value of these tests,[4][5] so the value of programmed electrical stimulation (PES) and inducibility remains controversial.
References
- ↑ Brugada J, Brugada R, Brugada P. Determinants of sudden cardiac death in individuals with the electrocardiographic pattern of Brugada syndrome and no previous cardiac arrest. Circulation. 2003; 108: 3092–3096.
- ↑ Brugada J, Brugada R, Antzelevitch C, Towbin J, Nademanee K, Brugada P (2002). "Long-term follow-up of individuals with the electrocardiographic pattern of right bundle-branch block and ST-segment elevation in precordial leads V1 to V3". Circulation. 105 (1): 73–8. PMID 11772879. Retrieved 2012-10-13. Unknown parameter
|month=ignored (help) - ↑ Brugada P, Brugada R, Mont L, Rivero M, Geelen P, Brugada J (2003). "Natural history of Brugada syndrome: the prognostic value of programmed electrical stimulation of the heart". Journal of Cardiovascular Electrophysiology. 14 (5): 455–7. PMID 12776858. Retrieved 2012-10-13. Unknown parameter
|month=ignored (help) - ↑ Priori SG, Napolitano C, Gasparini M, Pappone C, Della Bella P, Giordano U, Bloise R, Giustetto C, De Nardis R, Grillo M, Ronchetti E, Faggiano G, Nastoli J (2002). "Natural history of Brugada syndrome: insights for risk stratification and management". Circulation. 105 (11): 1342–7. PMID 11901046. Retrieved 2012-10-13. Unknown parameter
|month=ignored (help) - ↑ Eckardt L, Probst V, Smits JP, Bahr ES, Wolpert C, Schimpf R, Wichter T, Boisseau P, Heinecke A, Breithardt G, Borggrefe M, LeMarec H, Böcker D, Wilde AA (2005). "Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndrome". Circulation. 111 (3): 257–63. doi:10.1161/01.CIR.0000153267.21278.8D. PMID 15642768. Retrieved 2012-10-13. Unknown parameter
|month=ignored (help)