Brugada syndrome history and symptoms

Brugada syndrome Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Differentiating Brugada syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Examples of Type I Brugada Syndrome
Chest X Ray
Echocardiography or Ultrasound
Electrophysiologic Studies
Genetic Testing
Treatment
Treatment
Drugs to Avoid
Drugs to Preferably Avoid
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Brugada syndrome history and symptoms On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Brugada syndrome history and symptoms All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Brugada syndrome history and symptoms
CDC on Brugada syndrome history and symptoms
Brugada syndrome history and symptoms in the news
Blogs on Brugada syndrome history and symptoms
Directions to Hospitals Treating Brugada syndrome
Risk calculators and risk factors for Brugada syndrome history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Patients with Brugada syndrome will sometimes have a family history of sudden cardiac death, and symptoms of syncope, seizures, or agonal breathing. These symptoms most often come on either at rest or during sleep.

History

• Brugada syndrome is diagnosed when a Type 1 ST-segment elevation is observed in more than one right precordial lead (V1-V3), in the presence or absence of sodium channel blocking agent, in conjunction with one or more of the following:

1. Family history of sudden cardiac death (SCD) (<45 years old)
2. Documented ventricular fibrillation (VF)
3. Polymorphic ventricular tachycardia
4. Coved-type ECG changes in family members
5. Inducibility of ventricular tachycardia (VT) with programmed electrical stimulation (PES)

• The diagnosis is also considered positive when a Type 2 (saddleback pattern) or Type 3 ST-segment elevation is observed in more than one right precordial lead under baseline conditions and can be converted to the diagnostic Type 1 pattern occurs upon exposure to a sodium channel blocker.

Symptoms

These complications typically occur when an affected person is resting or asleep:

• Fainting
• Syncope
• Seizures
• Difficulty breathing
• Sudden death
• Agonal breathing