Altitude sickness natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Complications

• Coma
• High altitude cerebral edema (brain swelling). Severe instances of high altitude cerebral edema (HACE) can lead to death if not treated quickly.
• Pulmonary edema

Prognosis

Most cases are mild, and symptoms improve promptly with a return to lower altitude. Severe cases may result in death due to respiratory distress or brain swelling (cerebral edema). In remote locations, emergency evacuation may not be possible, or treatment may be delayed. These conditions could adversely affect the outcome.