WBR0085: Difference between revisions
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(Created page with "{{WBRQuestion |QuestionAuthor=Aditya Govindavarjhulla |ExamType=USMLE Step 1 |MainCategory=General Principles |SubCategory=Microbiology |MainCategory=General Principles |SubC...") |
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{{WBRQuestion | {{WBRQuestion | ||
|QuestionAuthor=Aditya Govindavarjhulla | |QuestionAuthor=Aditya Govindavarjhulla | ||
|ExamType=USMLE Step | |ExamType=USMLE Step 2 CK | ||
|MainCategory= | |MainCategory=Pediatrics | ||
|SubCategory= | |SubCategory=Infectious Disease, Pediatrics | ||
|MainCategory= | |MainCategory=Pediatrics | ||
|SubCategory= | |SubCategory=Infectious Disease, Pediatrics | ||
|MainCategory= | |MainCategory=Pediatrics | ||
|SubCategory= | |SubCategory=Infectious Disease, Pediatrics | ||
|MainCategory= | |MainCategory=Pediatrics | ||
|MainCategory=Pediatrics | |||
|SubCategory=Infectious Disease, Pediatrics | |||
|MainCategory=Pediatrics | |||
|SubCategory=Infectious Disease, Pediatrics | |||
|MainCategory=Pediatrics | |||
|SubCategory=Infectious Disease, Pediatrics | |||
|MainCategory=Pediatrics | |||
|SubCategory=Infectious Disease, Pediatrics | |||
|MainCategory=Pediatrics | |||
|MainCategory=Pediatrics | |||
|SubCategory=Infectious Disease, Pediatrics | |||
|Prompt=A 26 year old mother was seen by an Infectious disease consult team on the 2 second day after delivery. She has positive test results for VDRL and FTA-ABS. Which test should be ordered by the team before starting treatment in the infant? | |Prompt=A 26 year old mother was seen by an Infectious disease consult team on the 2 second day after delivery. She has positive test results for VDRL and FTA-ABS. Which test should be ordered by the team before starting treatment in the infant? | ||
|Explanation=Explanation: All infants born to mothers who have reactive non-treponemal and treponemal test results should be evaluated with a quantitative non-treponemal serologic test (RPR or VDRL) performed on infant serum, because umbilical cord blood can become contaminated with maternal blood and yield a false-positive result. Conducting a treponemal test (i.e., TP-PA, FTA-ABS, EIA, or chemiluminescence assay) on a newborn’s serum is not necessary. | |Explanation=Explanation: All infants born to mothers who have reactive non-treponemal and treponemal test results should be evaluated with a quantitative non-treponemal serologic test (RPR or VDRL) performed on infant serum, because umbilical cord blood can become contaminated with maternal blood and yield a false-positive result. Conducting a treponemal test (i.e., TP-PA, FTA-ABS, EIA, or chemiluminescence assay) on a newborn’s serum is not necessary. | ||
|AnswerA=Maternal serum – VDRL | |AnswerA=Maternal serum – VDRL | ||
|AnswerAExp=Quantitative tests must be performed on infants born to reactive mothers, rather than testing the mother. | |AnswerAExp=Quantitative tests must be performed on infants born to reactive mothers, rather than testing the mother. | ||
|AnswerB= Infant serum – VDRL | |AnswerB=Infant serum – VDRL | ||
|AnswerBExp=Infant serum-VDRL is a quantitative non-treponemal serologic test. Infant serum VDRl or RPR should be performed on infants born to reactive mothers. | |AnswerBExp=Infant serum-VDRL is a quantitative non-treponemal serologic test. Infant serum VDRl or RPR should be performed on infants born to reactive mothers. | ||
|AnswerC= Umbilical cord – VDRL | |AnswerC=Umbilical cord – VDRL | ||
|AnswerCExp=Umbilical cord blood cannot be tested due to maternal and fetal blood mixing, which may give false positive results. | |AnswerCExp=Umbilical cord blood cannot be tested due to maternal and fetal blood mixing, which may give false positive results. | ||
|AnswerD=Infant serum – FTA-ABS | |AnswerD=Infant serum – FTA-ABS | ||
|AnswerDExp=Infant serum FTA-ABS is a treponemal test and non-treponemal test (RPR and VDRL) should be performed on a infant of reactive mother. | |AnswerDExp=Infant serum FTA-ABS is a treponemal test and non-treponemal test (RPR and VDRL) should be performed on a infant of reactive mother. | ||
|RightAnswer=D | |RightAnswer=D | ||
|Approved=Yes | |Approved=Yes | ||
}} | }} |