Meningococcemia primary prevention: Difference between revisions
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Current vaccines have polysaccharides of groups A, C, Y, and W-135. No vaccine available presently for group B disease since the polysaccharide is not sufficiently immunogenic to produce a reliable antibody response in humans to be effective. | Current vaccines have polysaccharides of groups A, C, Y, and W-135. No vaccine available presently for group B disease since the polysaccharide is not sufficiently immunogenic to produce a reliable antibody response in humans to be effective. | ||
===Prophylaxis=== | ===Prophylaxis=== | ||
* [[Rifampin]] 600 mg PO q12h x 4 doses total or alternatively [[ciprofloxacin]] 500 mg PO x 1 in patients over 18 who cannot tolerate [[rifampin]] | * [[Rifampin]] 600 mg PO q12h x 4 doses total or alternatively [[ciprofloxacin]] 500 mg PO x 1 in patients over 18 who cannot tolerate [[rifampin]]. | ||
==References== | ==References== | ||
Revision as of 17:43, 25 February 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Primary Prevention
Current vaccines have polysaccharides of groups A, C, Y, and W-135. No vaccine available presently for group B disease since the polysaccharide is not sufficiently immunogenic to produce a reliable antibody response in humans to be effective.
Prophylaxis
- Rifampin 600 mg PO q12h x 4 doses total or alternatively ciprofloxacin 500 mg PO x 1 in patients over 18 who cannot tolerate rifampin.