Acanthocytosis overview: Difference between revisions
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In human biology and [[medicine]], the term refers to pathological [[red blood cell]]s, which are coarse and irregularly crenelated resembling many-pointed stars. They are seen on [[blood film]]s in, among others, [[lipid]] abnormalities, [[liver]] disease, [[chorea acanthocytosis]], [[McLeod syndrome]] and several inherited neurological disorders, such as [[neuroacanthocytosis]]. | In human biology and [[medicine]], the term refers to pathological [[red blood cell]]s, which are coarse and irregularly crenelated resembling many-pointed stars. They are seen on [[blood film]]s in, among others, [[lipid]] abnormalities, [[liver]] disease, [[chorea acanthocytosis]], [[McLeod syndrome]] and several inherited neurological disorders, such as [[neuroacanthocytosis]]. | ||
==Pathophysiology== | |||
The imbalance in membrane lipids due to various abnormalities mainly in the liver, cause cells to stiffen, wrinkle and form spicules. | |||
==References== | ==References== | ||
Revision as of 19:06, 27 February 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Acanthocytosis is a digestive disorder that is characterized by the absence of very low density lipoproteins (VLDL) and chylomicrons in the plasma. Acanthocyte is a general term meaning 'spiny cell'. AKA "spur cell" in more severe cases In human biology and medicine, the term refers to pathological red blood cells, which are coarse and irregularly crenelated resembling many-pointed stars. They are seen on blood films in, among others, lipid abnormalities, liver disease, chorea acanthocytosis, McLeod syndrome and several inherited neurological disorders, such as neuroacanthocytosis.
Pathophysiology
The imbalance in membrane lipids due to various abnormalities mainly in the liver, cause cells to stiffen, wrinkle and form spicules.