Gangrene pathophysiology: Difference between revisions
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==Dry Gangrene== | ==Dry Gangrene== | ||
If the blood flow is interrupted for a reason other than severe bacterial infection, the result is a case of dry gangrene. People with impaired peripheral blood flow, such as diabetics, are at greater risk of contracting dry gangrene. | If the blood flow is interrupted for a reason other than severe bacterial infection, the result is a case of dry gangrene. People with impaired peripheral blood flow, such as diabetics, are at greater risk of contracting dry gangrene.The dark coloration is due to liberation of [[hemoglobin]] from hemolyzed red blood cells which is acted upon by [[hydrogen sulfide]] (H<sub>2</sub>S) produced by the bacteria, resulting in formation of black iron sulfide that remains in the tissues<ref>[http://compepid.tuskegee.edu/syllabi/pathobiology/pathology/genpath/chapter3.html chapter 3.html<!-- Bot generated title -->]</ref>. | ||
==References== | ==References== | ||
Revision as of 20:50, 27 February 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Dry Gangrene
If the blood flow is interrupted for a reason other than severe bacterial infection, the result is a case of dry gangrene. People with impaired peripheral blood flow, such as diabetics, are at greater risk of contracting dry gangrene.The dark coloration is due to liberation of hemoglobin from hemolyzed red blood cells which is acted upon by hydrogen sulfide (H2S) produced by the bacteria, resulting in formation of black iron sulfide that remains in the tissues[1].