Familial mediterranean fever laboratory findings: Difference between revisions
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== | ==Overview== | ||
An [[acute phase response]] is present during attacks, with high [[C-reactive protein]] levels, an elevated [[white blood cell]] count and other markers of [[inflammation]]. In patients with a long history of attacks, monitoring the [[renal function]] is of importance in predicting [[chronic renal failure]].<ref name=Livneh/> | An [[acute phase response]] is present during attacks, with high [[C-reactive protein]] levels, an elevated [[white blood cell]] count and other markers of [[inflammation]]. In patients with a long history of attacks, monitoring the [[renal function]] is of importance in predicting [[chronic renal failure]].<ref name=Livneh/> | ||
Revision as of 21:32, 5 March 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
An acute phase response is present during attacks, with high C-reactive protein levels, an elevated white blood cell count and other markers of inflammation. In patients with a long history of attacks, monitoring the renal function is of importance in predicting chronic renal failure.[1]
A genetic test is also available now that the disease has been linked to mutations in the MEFV gene. Sequencing of exons 2, 3, 5, and 10 of this gene detects an estimated 97% of all known mutations.[1]