Alopecia medical therapy: Difference between revisions
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Created page with "__NOTOC__ {{Alopecia}} {{CMG}} ==Overview== == Pharmacotherapy == === Acute Pharmacotherapies === * Androgenetic alopecia *:* For men, oral finasteride or [[topic..." |
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__NOTOC__ | __NOTOC__ | ||
{{Alopecia}} | {{Alopecia}} | ||
{{CMG}} | {{CMG}} | ||
==Medical Therapy== | |||
== | ===Pharmacotherapy=== | ||
====Acute Pharmacotherapies==== | |||
== Pharmacotherapy == | |||
=== Acute Pharmacotherapies === | |||
* [[Androgenetic alopecia]] | * [[Androgenetic alopecia]] | ||
*:* For men, oral [[finasteride]] or [[topical]] [[minoxidil]] | *:* For men, oral [[finasteride]] or [[topical]] [[minoxidil]] | ||
| Line 22: | Line 17: | ||
*:* Intralesional [[steriod]] [[injections]] | *:* Intralesional [[steriod]] [[injections]] | ||
=== Chronic Pharmacotherapies === | ====Chronic Pharmacotherapies==== | ||
*Topical [[minoxidil]] ([[Rogaine]], generic): | *Topical [[minoxidil]] ([[Rogaine]], generic): | ||
:*only [[Rx]] approved for women as well as men | :*only [[Rx]] approved for women as well as men | ||
| Line 28: | Line 23: | ||
:*Mechanism unclear | :*Mechanism unclear | ||
*Efficacy: | *Efficacy: | ||
:* | :*Hair counts ~5x higher than placebo with use of 5% solution (men) | ||
:* | :*Hair counts 45% higher with use of 5% solution compared with use of 2% solution (men) | ||
:* | :*Hair counts returned to those of placebo group within 24 weeks after discontinuation [[Rx]] (men) | ||
:*women: increased hair growth in 60% vs. 40% with use of 2% soln vs. placebo | :*women: increased hair growth in 60% vs. 40% with use of 2% soln vs. placebo | ||
:*'''Advice for patients:''' | :*'''Advice for patients:''' | ||
::*1 mL bid applied to dry [[scalp]] with spray or dropper; spread lightly w/finger | ::*1 mL bid applied to dry [[scalp]] with spray or dropper; spread lightly w/finger | ||
::* | ::*Expect decreased loss w/in 2 mos, growth w/in 4-8 mos; stable at 1-1.5 yrs | ||
::* | ::*Best results if baldness present at vertex x < 5 years and < 10 cm diameter | ||
::*cosmetically notable growth occurs in only 30-40% | ::*cosmetically notable growth occurs in only 30-40% | ||
::*Rx must continue indefinitely or regrown hair will be lost | ::*Rx must continue indefinitely or regrown hair will be lost | ||
::*[[Side effect]]s = rare contact or irritant dermatitis; no change [[blood pressure]], [[heart rate]] or weight | ::*[[Side effect]]s = rare contact or irritant dermatitis; no change [[blood pressure]], [[heart rate]] or weight | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:primary care]] | |||
[[Category:Disease]] | |||
[[Category:Dermatology]] | |||
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Revision as of 14:16, 14 March 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Medical Therapy
Pharmacotherapy
Acute Pharmacotherapies
- Androgenetic alopecia
- For men, oral finasteride or topical minoxidil
- For women, antiandrogens if adrenal androgens are increased
- Tinea capitus/kerion
- Oral antifungals
- Alopecia areata
- Glucocorticoids
- Psoralen and ultraviolet A (PUVA)
- Superpotent steriods
- Cyclosporine
- Intralesional steriod injections
Chronic Pharmacotherapies
- Efficacy:
- Hair counts ~5x higher than placebo with use of 5% solution (men)
- Hair counts 45% higher with use of 5% solution compared with use of 2% solution (men)
- Hair counts returned to those of placebo group within 24 weeks after discontinuation Rx (men)
- women: increased hair growth in 60% vs. 40% with use of 2% soln vs. placebo
- Advice for patients:
- 1 mL bid applied to dry scalp with spray or dropper; spread lightly w/finger
- Expect decreased loss w/in 2 mos, growth w/in 4-8 mos; stable at 1-1.5 yrs
- Best results if baldness present at vertex x < 5 years and < 10 cm diameter
- cosmetically notable growth occurs in only 30-40%
- Rx must continue indefinitely or regrown hair will be lost
- Side effects = rare contact or irritant dermatitis; no change blood pressure, heart rate or weight
References