Malabsorption other diagnostic studies: Difference between revisions
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[[Image:Coeliac path.jpg|thumb|left|Biopsy of [[small bowel]] showing coeliac disease manifested by blunting of [[villi]], crypt hyperplasia, and [[lymphocyte]] infiltration of crypts.]] | [[Image:Coeliac path.jpg|thumb|left|Biopsy of [[small bowel]] showing coeliac disease manifested by blunting of [[villi]], crypt hyperplasia, and [[lymphocyte]] infiltration of crypts.]] | ||
*Endoscopy is frequently undertaken, but to | *Endoscopy is frequently undertaken, but to visualizing the small intestine, which can be up to 7m long, is indeed a daunting task. | ||
**[[OGD]] to reveal duodenal lesion also for D2 biopsy. (for [[celiac disease]], [[tropical sprue]], [[whipple disease]], [[abetalipoproteinemia]] etc) | **[[OGD]] to reveal duodenal lesion also for D2 biopsy. (for [[celiac disease]], [[tropical sprue]], [[whipple disease]], [[abetalipoproteinemia]] etc) | ||
**[[Enteroscopy]] for enteropathy and jejunal aspirate and culture for bacterial overgrowth. | **[[Enteroscopy]] for enteropathy and jejunal aspirate and culture for bacterial overgrowth. | ||
Revision as of 13:58, 1 April 2013
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Malabsorption |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Other Diagnostic Studies
Interventional Studies
- Endoscopy is frequently undertaken, but to visualizing the small intestine, which can be up to 7m long, is indeed a daunting task.
- OGD to reveal duodenal lesion also for D2 biopsy. (for celiac disease, tropical sprue, whipple disease, abetalipoproteinemia etc)
- Enteroscopy for enteropathy and jejunal aspirate and culture for bacterial overgrowth.
- Colonoscopy is helpful in colonic or ileal lesion.
- ERCP: MRCP to complement or as an alternative to ERCP.
Other Investigations
- Radio isotope tests e.g. 75SeHCAT, 95mTc to exclude terminal ileal disease.
- Sugar probes or sub 51Cr-EDTA to determine intestinal permeability.[1]
- Glucose hydrogen breath test for bacterial overgrowth.
- D-xylose absorption test: Lower level in urine after ingestion indicates bacterial overgrowth or reduced absorptive surface, normal in pancreatic insufficiency.
- Bile salt breath test to determine bile salt malabsorption.
- Schilling test to establish cause of B12 deficiency.
- Lactose H2 breath test for lactose intolerance.