Cryptorchidism physical examination: Difference between revisions
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The most common diagnostic dilemma in otherwise normal boys is distinguishing a retractile testis from a [[testis]] that will not/cannot descend spontaneously into the [[scrotum]]. Retractile testes are more common than truly undescended testes and do not need to be operated on. In normal males, as the [[cremaster muscle]] relaxes or contracts, the testis moves lower or higher ("retracts") in the scrotum. This [[cremasteric reflex]] is much more active in infant boys than older men. A retractile testis high in the scrotum can be difficult to distinguish from a position in the lower inguinal canal. Though there are various maneuvers used to do so, such as using a crosslegged position, soaping the examiner's fingers, or examining in a warm bath, the benefit of surgery in these cases can be a matter of clinical judgement. | The most common diagnostic dilemma in otherwise normal boys is distinguishing a retractile testis from a [[testis]] that will not/cannot descend spontaneously into the [[scrotum]]. Retractile testes are more common than truly undescended testes and do not need to be operated on. In normal males, as the [[cremaster muscle]] relaxes or contracts, the testis moves lower or higher ("retracts") in the scrotum. This [[cremasteric reflex]] is much more active in infant boys than older men. A retractile testis high in the scrotum can be difficult to distinguish from a position in the lower inguinal canal. Though there are various maneuvers used to do so, such as using a crosslegged position, soaping the examiner's fingers, or examining in a warm bath, the benefit of surgery in these cases can be a matter of clinical judgement. | ||
In the minority of cases with bilaterally non-palpable testes, further testing to locate the testes, assess their function, and exclude additional problems is often useful. Pelvic [[ultrasound]] or [[magnetic resonance imaging]] can often, but not invariably, locate the testes while confirming absence of a uterus. A [[karyotype]] can confirm or exclude forms of dysgenetic primary [[hypogonadism]], such as [[Klinefelter syndrome]] or [[mixed gonadal dysgenesis]]. | In the minority of cases with bilaterally non-palpable testes, further testing to locate the testes, assess their function, and exclude additional problems is often useful. Pelvic [[ultrasound]] or [[magnetic resonance imaging]] can often, but not invariably, locate the testes while confirming absence of a [[uterus]]. A [[karyotype]] can confirm or exclude forms of dysgenetic primary [[hypogonadism]], such as [[Klinefelter syndrome]] or [[mixed gonadal dysgenesis]]. | ||
[[Hormone]] levels (especially [[gonadotropins]] and AMH) can help confirm that there are hormonally functional testes worth attempting to rescue, as can stimulation with a few injections of [[human chorionic gonadotropin]] to elicit a rise of the [[testosterone]] level. Occasionally these tests reveal an unsuspected and more complicated [[intersex]]condition. | [[Hormone]] levels (especially [[gonadotropins]] and AMH) can help confirm that there are hormonally functional testes worth attempting to rescue, as can stimulation with a few injections of [[human chorionic gonadotropin]] to elicit a rise of the [[testosterone]] level. Occasionally these tests reveal an unsuspected and more complicated [[intersex]]condition. | ||
Revision as of 23:17, 12 April 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saumya Easaw, M.B.B.S.[2]
Overview
The most common diagnostic dilemma in otherwise normal boys is distinguishing a retractile testis from a testis that will not/cannot descend spontaneously into the scrotum. Retractile testes are more common than truly undescended testes and do not need to be operated on. In normal males, as the cremaster muscle relaxes or contracts, the testis moves lower or higher ("retracts") in the scrotum. This cremasteric reflex is much more active in infant boys than older men. A retractile testis high in the scrotum can be difficult to distinguish from a position in the lower inguinal canal. Though there are various maneuvers used to do so, such as using a crosslegged position, soaping the examiner's fingers, or examining in a warm bath, the benefit of surgery in these cases can be a matter of clinical judgement.
In the minority of cases with bilaterally non-palpable testes, further testing to locate the testes, assess their function, and exclude additional problems is often useful. Pelvic ultrasound or magnetic resonance imaging can often, but not invariably, locate the testes while confirming absence of a uterus. A karyotype can confirm or exclude forms of dysgenetic primary hypogonadism, such as Klinefelter syndrome or mixed gonadal dysgenesis. Hormone levels (especially gonadotropins and AMH) can help confirm that there are hormonally functional testes worth attempting to rescue, as can stimulation with a few injections of human chorionic gonadotropin to elicit a rise of the testosterone level. Occasionally these tests reveal an unsuspected and more complicated intersexcondition.
In the even smaller minority of cryptorchid infants who have other obvious birth defects of the genitalia, further testing is crucial and has a high likelihood of detecting anintersex condition or other anatomic anomalies. Ambiguity can indicate either impaired androgen synthesis or reduced sensitivity. The presence of a uterus by pelvic ultrasound suggests either persistent müllerian duct syndrome (AMH deficiency or insensitivity) or a severely virilized genetic female with congenital adrenal hyperplasia. An unambiguous micropenis, especially accompanied by hypoglycemia or jaundice, suggests congenitalhypopituitarism.