High density lipoprotein causes: Difference between revisions
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* [[Insulin resistance]] | * [[Insulin resistance]] | ||
* [[Diabetes mellitus]] | * [[Diabetes mellitus]] | ||
* [[Metabolic syndrome]] | * [[Metabolic syndrome]]<ref name="pmid23564803">{{cite journal |author=Elme A, Utriainen M, Kellokumpu-Lehtinen P, ''et al.'' |title=Obesity and physical inactivity are related to impaired physical health of breast cancer survivors |journal=Anticancer Res. |volume=33 |issue=4 |pages=1595–602 |year=2013 |month=April |pmid=23564803 |doi= |url=}}</ref> | ||
* Drugs | * Drugs | ||
# [[Beta-blocker]]s | # [[Beta-blocker]]s | ||
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* Liver disease | * Liver disease | ||
* [[Menopause]] | * [[Menopause]] | ||
* [[Obesity]] | * [[Obesity]]<ref name="pmid23564803">{{cite journal |author=Elme A, Utriainen M, Kellokumpu-Lehtinen P, ''et al.'' |title=Obesity and physical inactivity are related to impaired physical health of breast cancer survivors |journal=Anticancer Res. |volume=33 |issue=4 |pages=1595–602 |year=2013 |month=April |pmid=23564803 |doi= |url=}}</ref> | ||
* Puberty in males | * Puberty in males | ||
* [[Uremia]] | * [[Uremia]] | ||
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* Elevated [[CETP]] (cholesteryl ester transfer protein) activity: Polymorphism of the gene TaqIB (CETP gene) is known to be associated with variations in the plasma concentrations of CETP. A gene variant called TaqIB1 is associated with a higher CETP concentration and lower HDL-C levels in the plasma. Two other mutations that result in similar findings are A373P and R451Q. | * Elevated [[CETP]] (cholesteryl ester transfer protein) activity: Polymorphism of the gene TaqIB (CETP gene) is known to be associated with variations in the plasma concentrations of CETP. A gene variant called TaqIB1 is associated with a higher CETP concentration and lower HDL-C levels in the plasma. Two other mutations that result in similar findings are A373P and R451Q. | ||
* Smoking | * Smoking | ||
* Lack of physical exercise | * Lack of physical exercise<ref name="pmid23564803">{{cite journal |author=Elme A, Utriainen M, Kellokumpu-Lehtinen P, ''et al.'' |title=Obesity and physical inactivity are related to impaired physical health of breast cancer survivors |journal=Anticancer Res. |volume=33 |issue=4 |pages=1595–602 |year=2013 |month=April |pmid=23564803 |doi= |url=}}</ref> | ||
* High carbohydrate diet | * High carbohydrate diet | ||
Revision as of 17:16, 15 April 2013
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High Density Lipoprotein Microchapters |
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Diagnosis |
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Treatment |
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Clinical Trials |
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Case Studies |
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High density lipoprotein causes On the Web |
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American Roentgen Ray Society Images of High density lipoprotein causes |
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Risk calculators and risk factors for High density lipoprotein causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]; Raviteja Guddeti, M.B.B.S. [3]
Causes
- HDL cholesterol is a positive cardiac risk factor if
- HDL < 35 mg/dL
- Total cholesterol to HDL ratio in > 5.0 (in men)
- Total cholesterol to HDL ratio in > 4.5 (in women)
- Negative cardiac risk factor if HDL > 60 mg/dL
Decreased
- Apolipoprotein deficiency: Hypoalphalipoproteinemia can be of three types.
- Impaired synthesis of apo A-1: apo A-I deficiency, apo A-1/C-3 deficiency, apo A-1 structural variants
- Increased catabolism: familial HDL deficiency or Tangier disease
- Enzymatic changes: genetic, reduced activity of lipoprotein lipase, elevated liver triglyceride lipase activity, LCAT (lecithin cholesterol acyltransferase) deficiency
- Liver disease
- Menopause
- Obesity[1]
- Puberty in males
- Uremia
- Familial combined hypolipidemia
- Elevated CETP (cholesteryl ester transfer protein) activity: Polymorphism of the gene TaqIB (CETP gene) is known to be associated with variations in the plasma concentrations of CETP. A gene variant called TaqIB1 is associated with a higher CETP concentration and lower HDL-C levels in the plasma. Two other mutations that result in similar findings are A373P and R451Q.
- Smoking
- Lack of physical exercise[1]
- High carbohydrate diet
Increased
- Drugs
- Moderate alcohol intake
- Regular aerobic exercise
- Weight loss