High density lipoprotein epidemiology and demographics: Difference between revisions
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==Epidemiology== | ==Epidemiology and Demographics== | ||
Epidemiological studies have shown that high concentrations of HDL (over 60 mg/dL) have protective value against [[cardiovascular disease]]s such as ischemic [[stroke]] and [[myocardial infarction]]. Low concentrations of HDL (below 40 mg/dL for men, below 50 mg/dL for women) are a positive risk factor for these atherosclerotic diseases. | Epidemiological studies have shown that high concentrations of HDL (over 60 mg/dL) have protective value against [[cardiovascular disease]]s such as ischemic [[stroke]] and [[myocardial infarction]]. Low concentrations of HDL (below 40 mg/dL for men, below 50 mg/dL for women) are a positive risk factor for these atherosclerotic diseases. | ||
Data from the landmark [[Framingham Heart Study]] showed that for a given level of LDL, the risk of heart disease increases 10-fold as the HDL varies from high to low. Conversely, for a fixed level of HDL, the risk increases 3-fold as LDL varies from low to high. | Data from the landmark [[Framingham Heart Study]] showed that for a given level of LDL, the risk of heart disease increases 10-fold as the HDL varies from high to low. Conversely, for a fixed level of HDL, the risk increases 3-fold as LDL varies from low to high. | ||
===Gender=== | |||
Men tend to have noticeably lower HDL levels, with smaller size and lower cholesterol content, than women. Men also have an increased incidence of [[atherosclerosis|atherosclerotic]] heart disease. | Men tend to have noticeably lower HDL levels, with smaller size and lower cholesterol content, than women. Men also have an increased incidence of [[atherosclerosis|atherosclerotic]] heart disease. | ||
Revision as of 20:19, 26 April 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]; Raviteja Guddeti, M.B.B.S. [3]
Epidemiology and Demographics
Epidemiological studies have shown that high concentrations of HDL (over 60 mg/dL) have protective value against cardiovascular diseases such as ischemic stroke and myocardial infarction. Low concentrations of HDL (below 40 mg/dL for men, below 50 mg/dL for women) are a positive risk factor for these atherosclerotic diseases.
Data from the landmark Framingham Heart Study showed that for a given level of LDL, the risk of heart disease increases 10-fold as the HDL varies from high to low. Conversely, for a fixed level of HDL, the risk increases 3-fold as LDL varies from low to high.
Gender
Men tend to have noticeably lower HDL levels, with smaller size and lower cholesterol content, than women. Men also have an increased incidence of atherosclerotic heart disease.