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{{Template:Myalgia}}
{{Template:Myalgia}}
{{CMG}}
{{CMG}}
== Overview ==
== Causes ==
== Causes ==
 
===Common Causes===
The most common causes of myalgia are overuse, [[injury]] or [[Stress (medicine)|stress]]<ref name=MedlinePlus>[http://www.nlm.nih.gov/medlineplus/ency/article/003178.htm MedlinePlus]</ref>. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination and withdrawal syndromes.
The most common causes of myalgia are overuse, [[injury]] or [[Stress (medicine)|stress]]<ref name=MedlinePlus>[http://www.nlm.nih.gov/medlineplus/ency/article/003178.htm MedlinePlus]</ref>. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination and withdrawal syndromes.


=== Overuse ===
==== Overuse ====


Overuse of a muscle is using it too much, too soon and/or too often. <ref name=MedlinePlus/>  Examples are:
Overuse of a muscle is using it too much, too soon and/or too often. <ref name=MedlinePlus/>  Examples are:
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* [[Repetitive strain injury]].
* [[Repetitive strain injury]].


=== Injury ===
==== Injury ====


The most common causes of myalgia by [[injury]] are: sprains and strain (injury)<ref name=MedlinePlus/>.
The most common causes of myalgia by [[injury]] are: sprains and strain (injury)<ref name=MedlinePlus/>.


=== Diseases/Disorders ===
==== Diseases/Disorders ====


==== Infectious ====
===== Infectious =====


[[Trichinosis]], [[Typhoid fever]], [[Upper respiratory tract infection]], [[Viral pneumonia]], [[Influenza]], [[Common cold]], [[Community-acquired pneumonia]], [[Coccidioidomycosis]], [[Dengue]], [[Endemic typhus]], [[HIV]], [[Infectious mononucleosis]], [[Legionellosis]], [[Leptospirosis]], [[Lyme disease]], [[Malaria]], [[Marburg virus]], [[Meningitis]], [[Monkeypox]], [[Pharyngitis]], [[Pneumonia]], [[Prostatitis]], [[Psittacosis]], [[Q fever]], [[Rabies]],  [[Rift Valley fever]], [[Severe acute respiratory syndrome]] (SARS), [[Toxic shock syndrome]], West Nile, [[Chikungunya]]
[[Trichinosis]], [[Typhoid fever]], [[Upper respiratory tract infection]], [[Viral pneumonia]], [[Influenza]], [[Common cold]], [[Community-acquired pneumonia]], [[Coccidioidomycosis]], [[Dengue]], [[Endemic typhus]], [[HIV]], [[Infectious mononucleosis]], [[Legionellosis]], [[Leptospirosis]], [[Lyme disease]], [[Malaria]], [[Marburg virus]], [[Meningitis]], [[Monkeypox]], [[Pharyngitis]], [[Pneumonia]], [[Prostatitis]], [[Psittacosis]], [[Q fever]], [[Rabies]],  [[Rift Valley fever]], [[Severe acute respiratory syndrome]] (SARS), [[Toxic shock syndrome]], West Nile, [[Chikungunya]]


==== Autoimmune ====
===== Autoimmune =====


[[Multiple sclerosis]], [[Myositis]], [[Lupus erythematosus]], [[Familial Mediterranean fever]], [[Polyarteritis nodosa]], [[Devic's disease]], [[Morphea]]
[[Multiple sclerosis]], [[Myositis]], [[Lupus erythematosus]], [[Familial Mediterranean fever]], [[Polyarteritis nodosa]], [[Devic's disease]], [[Morphea]]


==== Metabolic defect ====
===== Metabolic Defect =====


[[Carnitine palmitoyltransferase II deficiency]], [[Conn's syndrome]], [[Adrenal insufficiency]]
[[Carnitine palmitoyltransferase II deficiency]], [[Conn's syndrome]], [[Adrenal insufficiency]]


==== Other ====
===== Other =====


[[Chronic fatigue syndrome]], [[Hypokalemia]], [[Exercise intolerance]], [[Mastocytosis]], [[Peripheral neuropathy]], Eosinophilia myalgia syndrome, [[Fibromyalgia]], [[Barcoo Fever]], [[Delayed onset muscle soreness]]
[[Chronic fatigue syndrome]], [[Hypokalemia]], [[Exercise intolerance]], [[Mastocytosis]], [[Peripheral neuropathy]], Eosinophilia myalgia syndrome, [[Fibromyalgia]], [[Barcoo Fever]], [[Delayed onset muscle soreness]]


=== Medications ===
==== Medications====


Aldara, [[Acrylamide]], [[Darbepoetin]], [[Isotretinoin]], [[Procainamide]], [[Quinupristin/dalfopristin]], Spiriva, [[Sumatriptan]], [[Vardenafil]], [[Statins]], Zetia, Zomig, Boniva
Aldara, [[Acrylamide]], [[Darbepoetin]], [[Isotretinoin]], [[Procainamide]], [[Quinupristin/dalfopristin]], Spiriva, [[Sumatriptan]], [[Vardenafil]], [[Statins]], Zetia, Zomig, Boniva


=== As a Response to Vaccination ===
==== As a Response to Vaccination ====


A moderate occurrence (25-35%) of myalgia in recipients of [[tetanus]] [[vaccination]] is identified in the US; it presents in the large muscle groups and at the subcutaneous injection site.  When a patient returns with these symptoms (which include [[fever]], poor [[appetite]] and [[lethargy]]), a clinician who fails to notice the recent tetanus vaccination on the patient's chart is in danger of making a life-threatening misdiagnosis.
A moderate occurrence (25-35%) of myalgia in recipients of [[tetanus]] [[vaccination]] is identified in the US; it presents in the large muscle groups and at the subcutaneous injection site.  When a patient returns with these symptoms (which include [[fever]], poor [[appetite]] and [[lethargy]]), a clinician who fails to notice the recent tetanus vaccination on the patient's chart is in danger of making a life-threatening misdiagnosis.
An item of note is that in heart patients using selective β<sub>1</sub>-blockers such as [[metoprolol]], incidence of myalgia after tetanus vaccination is significantly higher.
An item of note is that in heart patients using selective β<sub>1</sub>-blockers such as [[metoprolol]], incidence of myalgia after tetanus vaccination is significantly higher.


=== Withdrawal Syndromes ===
==== Withdrawal Syndromes ====


Sudden cessation of [[opioids]], [[barbiturates]], [[benzodiazepines]], or [[alcohol]] can induce myalgia.
Sudden cessation of [[opioids]], [[barbiturates]], [[benzodiazepines]], or [[alcohol]] can induce myalgia.
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== References ==
== References ==
{{reflist|2}}
{{reflist|2}}
 
[[Category:Orthopedics]]
[[Category:Rheumatology]]
[[Category:Signs and symptoms]]
[[Category:Primary care]]
{{WH}}
{{WH}}


{{WS}}
{{WS}}

Revision as of 18:33, 1 May 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

Common Causes

The most common causes of myalgia are overuse, injury or stress[1]. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination and withdrawal syndromes.

Overuse

Overuse of a muscle is using it too much, too soon and/or too often. [1] Examples are:

Injury

The most common causes of myalgia by injury are: sprains and strain (injury)[1].

Diseases/Disorders

Infectious

Trichinosis, Typhoid fever, Upper respiratory tract infection, Viral pneumonia, Influenza, Common cold, Community-acquired pneumonia, Coccidioidomycosis, Dengue, Endemic typhus, HIV, Infectious mononucleosis, Legionellosis, Leptospirosis, Lyme disease, Malaria, Marburg virus, Meningitis, Monkeypox, Pharyngitis, Pneumonia, Prostatitis, Psittacosis, Q fever, Rabies, Rift Valley fever, Severe acute respiratory syndrome (SARS), Toxic shock syndrome, West Nile, Chikungunya

Autoimmune

Multiple sclerosis, Myositis, Lupus erythematosus, Familial Mediterranean fever, Polyarteritis nodosa, Devic's disease, Morphea

Metabolic Defect

Carnitine palmitoyltransferase II deficiency, Conn's syndrome, Adrenal insufficiency

Other

Chronic fatigue syndrome, Hypokalemia, Exercise intolerance, Mastocytosis, Peripheral neuropathy, Eosinophilia myalgia syndrome, Fibromyalgia, Barcoo Fever, Delayed onset muscle soreness

Medications

Aldara, Acrylamide, Darbepoetin, Isotretinoin, Procainamide, Quinupristin/dalfopristin, Spiriva, Sumatriptan, Vardenafil, Statins, Zetia, Zomig, Boniva

As a Response to Vaccination

A moderate occurrence (25-35%) of myalgia in recipients of tetanus vaccination is identified in the US; it presents in the large muscle groups and at the subcutaneous injection site. When a patient returns with these symptoms (which include fever, poor appetite and lethargy), a clinician who fails to notice the recent tetanus vaccination on the patient's chart is in danger of making a life-threatening misdiagnosis. An item of note is that in heart patients using selective β1-blockers such as metoprolol, incidence of myalgia after tetanus vaccination is significantly higher.

Withdrawal Syndromes

Sudden cessation of opioids, barbiturates, benzodiazepines, or alcohol can induce myalgia.

References

Template:WH

Template:WS