Fibroadenoma pathophysiology: Difference between revisions
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{{Fibroadenoma}} | {{Fibroadenoma}} | ||
{{CMG}} | {{CMG}} | ||
==Pathophysiology== | ==Pathophysiology== | ||
Depending on the amount and the relationship between these two components, there are two main histological features: intracanalicular and pericanalicular. Often, both types are found in the same tumor. Intracanalicular fibroadenoma: stromal proliferation predominates and compresses the ducts, which are irregular, reduced to slits. Pericanalicular fibroadenoma: fibrous stroma proliferates around the ductal spaces, so that they remain round or oval, on cross section. The basement membrane is intact. [http://www.pathologyatlas.ro/Fibroadenoma.html 1] | Depending on the amount and the relationship between these two components, there are two main histological features: intracanalicular and pericanalicular. Often, both types are found in the same tumor. Intracanalicular fibroadenoma: stromal proliferation predominates and compresses the ducts, which are irregular, reduced to slits. Pericanalicular fibroadenoma: fibrous stroma proliferates around the ductal spaces, so that they remain round or oval, on cross section. The basement membrane is intact. [http://www.pathologyatlas.ro/Fibroadenoma.html 1] | ||
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===Microscopically=== | ===Microscopically=== | ||
The epithelial proliferation describes duct-like spaces surrounded by a fibroblastic stroma. The proliferated epithelium is typical. | The epithelial proliferation describes duct-like spaces surrounded by a fibroblastic stroma. The proliferated epithelium is typical. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{Soft tissue tumors and sarcomas}} | {{Soft tissue tumors and sarcomas}} | ||
[[Category:Breast]] | [[Category:Breast]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Primary care]] | |||
{{WH}} | |||
{{WS}} | |||
Revision as of 15:36, 2 May 2013
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Fibroadenoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Fibroadenoma pathophysiology On the Web |
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American Roentgen Ray Society Images of Fibroadenoma pathophysiology |
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Risk calculators and risk factors for Fibroadenoma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Pathophysiology
Depending on the amount and the relationship between these two components, there are two main histological features: intracanalicular and pericanalicular. Often, both types are found in the same tumor. Intracanalicular fibroadenoma: stromal proliferation predominates and compresses the ducts, which are irregular, reduced to slits. Pericanalicular fibroadenoma: fibrous stroma proliferates around the ductal spaces, so that they remain round or oval, on cross section. The basement membrane is intact. 1
Macroscopically
The tumor is round, elastic, nodular, and encapsulated (well circumscribed); on cut surface it is grey-white.
Microscopically
The epithelial proliferation describes duct-like spaces surrounded by a fibroblastic stroma. The proliferated epithelium is typical.