Neonatal jaundice natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
==Natural history | ==Natural history== | ||
===Complications=== | ===Complications=== | ||
With high doses of bilirubin (severe hyperbilirubinemia) there can be a complication known as [[kernicterus]]. This is the chief condition that treatment of jaundice is aimed at preventing. The effects of kernicterus range from fever, seizures, and a high-pitched crying to mental retardation. This is due to a staining effect on the [[basal ganglia]] leading to neuronal damage. With aggressive treatment such as exchange transfusion to lower very high bilirubin levels, the neurological effects are almost always transient. | With high doses of bilirubin (severe hyperbilirubinemia) there can be a complication known as [[kernicterus]]. This is the chief condition that treatment of jaundice is aimed at preventing. The effects of kernicterus range from fever, seizures, and a high-pitched crying to mental retardation. This is due to a staining effect on the [[basal ganglia]] leading to neuronal damage. With aggressive treatment such as exchange transfusion to lower very high bilirubin levels, the neurological effects are almost always transient. | ||
Revision as of 16:18, 21 May 2013
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Overview
Natural history
Complications
With high doses of bilirubin (severe hyperbilirubinemia) there can be a complication known as kernicterus. This is the chief condition that treatment of jaundice is aimed at preventing. The effects of kernicterus range from fever, seizures, and a high-pitched crying to mental retardation. This is due to a staining effect on the basal ganglia leading to neuronal damage. With aggressive treatment such as exchange transfusion to lower very high bilirubin levels, the neurological effects are almost always transient.