Leukocyte alkaline phosphatase: Difference between revisions
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*[[Cholangitis]] | *[[Cholangitis]] | ||
*[[Cholecystitis]] | *[[Cholecystitis]] | ||
*[[ | *Chronic [[anxiety]] state | ||
*[[ | *Chronic idiopathic [[neutrophilia]] | ||
*[[Chronic neutrophilic leukemia]] | *[[Chronic neutrophilic leukemia]] | ||
*[[Cigarette smoking]] | *[[Cigarette smoking]] | ||
*[[Clostridium difficile]] | *[[Clostridium difficile]] | ||
*[[Coccidioides immitis]] | *[[Coccidioides immitis]] | ||
*[[ | *Congenital [[asplenia]] | ||
*[[ | *Congenital [[neutropenia ]] | ||
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*[[Fanconi anemia]] | *[[Fanconi anemia]] | ||
*[[G-CSF]] | *[[G-CSF]] | ||
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*[[Hepatic necrosis]] | *[[Fulminant hepatic necrosis|Hepatic necrosis]] | ||
*[[Hereditary neutrophilia]] | *[[Hereditary neutrophilia]] | ||
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*[[ | *Major [[tissue]] injury | ||
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*[[Megaloblastic anemia]] | *[[Megaloblastic anemia]] | ||
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*[[Phenacetin]] | *[[Phenacetin]] | ||
*[[ | *Physical [[stress]] | ||
*[[Plague]] | *[[Plague]] | ||
*[[Poliomyelitis]] | *[[Poliomyelitis]] | ||
*[[Polycythemia vera]] | *[[Polycythemia vera]] | ||
*[[Post | *[[Splenectomy|Post splenectomy ]] | ||
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Revision as of 15:17, 17 July 2013
| Leukocyte alkaline phosphatase |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Vendhan Ramanujam M.B.B.S [2]
Synonyms and keywords: LAP
Overview
Leukocyte alkaline phosphatase is an enzyme found within white blood cells. The blood level of leukocyte alkaline phosphatase is measured in order to help in the diagnosis of certain conditions. Higher levels of the enzyme are seen in polycythemia vera, essential thrombocytosis, primary myelofibrosis and leukemoid reaction. Lower levels are found in chronic myelogenous leukemia, aplastic anemia, paroxysmal nocturnal hemoglobinuria and acute myelogenous leukemia.
Causes of Increased Leukocyte Alkaline Phosphatase
Common Causes
- Acute leukemia
- Aplastic Anemia
- Malignant lymphomas
- Megaloblastic anemia
- Multiple Myeloma[1]
- Myelofibrosis
- Polycythemia Vera
- Solid tumors
- Tissue necrosis[2][3]
Causes by Organ System
Causes in Alphabetical Order
Causes of Decreased Leukocyte Alkaline Phosphatase[4][5]
Common Causes
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
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References
- ↑ Brook J, Dreisbach PB (1977). "Leukocyte alkaline phosphatase levels in multiple myeloma". J Lab Clin Med. 90 (1): 114–7. PMID 406335.
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X