Faget's sign: Difference between revisions
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==Overview== | ==Overview== | ||
Faget's [[sign (medicine)|sign]] is the unusual constellation of [[fever]] and [[bradycardia]]. | Faget's [[sign (medicine)|sign]] is the unusual constellation of [[fever]] and [[bradycardia]]. | ||
==Historical Perspective== | |||
Feget's sign is named after [[Jean Charles Faget]], who characterized it in 1859.<ref>Jean-Charles Faget. Études médicale de quelques questions importantes pour la Louisiane, et exposé succinct d’une endémie paludéenne de forme catarrhale qui a sévi à la Nouvelle-Orléans, particulièrement sur les enfants, pendant l’epidémie de fièvre jaune de 1858. New Orleans, 1859.</ref><ref name="www.whonamedit.com">{{Cite web | last = | first = | title = Whonamedit - Faget's sign | url = http://www.whonamedit.com/synd.cfm/3753.html | publisher = | date = | accessdate = 14 July 2013 }}</ref> | |||
==Pathophysiology== | ==Pathophysiology== | ||
In general, [[fever]] is accompanied by [[tachycardia]] rather than [[bradycardia]]. In fact, for each increase in temperature of one degree Fahrenheit, there is a commensurate increase in the [[heart rate]] of 10 beats/min. This relationship between increase in temperature and increase in heart rate is known as Liebermeister's rule.<ref name="Cunha-2000">{{Cite journal | last1 = Cunha | first1 = BA. | title = The diagnostic significance of relative bradycardia in infectious disease. | journal = Clin Microbiol Infect | volume = 6 | issue = 12 | pages = 633-4 | month = Dec | year = 2000 | doi = | PMID = 11284920 }}</ref> When [[fever]] is associated with [[bradyacrdia]] it is refered to as the Faget's sign. | In general, [[fever]] is accompanied by [[tachycardia]] rather than [[bradycardia]]. In fact, for each increase in temperature of one degree Fahrenheit, there is a commensurate increase in the [[heart rate]] of 10 beats/min. This relationship between increase in temperature and increase in heart rate is known as Liebermeister's rule.<ref name="Cunha-2000">{{Cite journal | last1 = Cunha | first1 = BA. | title = The diagnostic significance of relative bradycardia in infectious disease. | journal = Clin Microbiol Infect | volume = 6 | issue = 12 | pages = 633-4 | month = Dec | year = 2000 | doi = | PMID = 11284920 }}</ref> When [[fever]] is associated with [[bradyacrdia]] it is refered to as the Faget's sign. | ||
==Causes== | ==Causes== | ||
Revision as of 14:21, 21 July 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Template:GCC
Overview
Faget's sign is the unusual constellation of fever and bradycardia.
Historical Perspective
Feget's sign is named after Jean Charles Faget, who characterized it in 1859.[1][2]
Pathophysiology
In general, fever is accompanied by tachycardia rather than bradycardia. In fact, for each increase in temperature of one degree Fahrenheit, there is a commensurate increase in the heart rate of 10 beats/min. This relationship between increase in temperature and increase in heart rate is known as Liebermeister's rule.[3] When fever is associated with bradyacrdia it is refered to as the Faget's sign.
Causes
Common Causes
Faget's sign is commonly seen among patients with yellow fever. Other common causes of Feget's sign include the following:
- Brucellosis
- Chlamydia[4]
- Colorado tick fever virus
- Coxiella burnetii
- Dengue Fever[5]
- Drug fever (eg, Beta-blockers)
- Legionella[4][6]
- Leptospirosis
- Leishmaniasis
- Mycoplasma[4]
- Psittacosis
- Tularemia
- Typhoid fever
- Yellow Fever[3][7]
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Beta blocker, drug fever |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | Cyclic neutropenia |
| Hematologic | Babesiosis, cyclic neutropenia, lymphoma, malaria |
| Iatrogenic | No underlying causes |
| Infectious Disease | Atypical pneumonia, babesiosis, brucellosis, campylobacter fetus, chagas disease, chlamydia, chlamydophila psittaci, colorado tick fever virus, coxiella burnetii, cytomegalovirus mononucleosis, dengue fever, ehrlichia canis, enteric fever, francisella tularensis, group A streptococcus, Guanarito virus, Junin virus, Legionnaires' disease, leishmaniasis, leptospirosis, listeria monocytogenes, Machupo virus, malaria, mycoplasma, orientia tsutsugamushi, plasmodium vivax , Q fever, rickettsiosis, rickettsia typhi, rocky mountain spotted fever, salmonella enterica, typhoid fever, viral hemorrhagic fever, yellow fever |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | Central nevous system lesion |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | Lymphoma |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | Atypical pneumonia |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | Anaphylaxis |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | Factitious fever |
Causes in Alphabetical Order
References
- ↑ Jean-Charles Faget. Études médicale de quelques questions importantes pour la Louisiane, et exposé succinct d’une endémie paludéenne de forme catarrhale qui a sévi à la Nouvelle-Orléans, particulièrement sur les enfants, pendant l’epidémie de fièvre jaune de 1858. New Orleans, 1859.
- ↑ "Whonamedit - Faget's sign". Retrieved 14 July 2013.
- ↑ 3.0 3.1 Cunha, BA. (2000). "The diagnostic significance of relative bradycardia in infectious disease". Clin Microbiol Infect. 6 (12): 633–4. PMID 11284920. Unknown parameter
|month=ignored (help) - ↑ 4.0 4.1 4.2 Johnson, DH.; Cunha, BA. (1993). "Atypical pneumonias. Clinical and extrapulmonary features of Chlamydia, Mycoplasma, and Legionella infections". Postgrad Med. 93 (7): 69–72, 75–6, 79–82. PMID 8493198. Unknown parameter
|month=ignored (help) - ↑ Senanayake, S. (2006). "Dengue fever and dengue haemorrhagic fever--a diagnostic challenge". Aust Fam Physician. 35 (8): 609–12. PMID 16894436. Unknown parameter
|month=ignored (help) - ↑ Erdogan, H.; Erdogan, A.; Lakamdayali, H.; Yilmaz, A.; Arslan, H. (2010). "Travel-associated Legionnaires disease: clinical features of 17 cases and a review of the literature". Diagn Microbiol Infect Dis. 68 (3): 297–303. doi:10.1016/j.diagmicrobio.2010.07.023. PMID 20955914. Unknown parameter
|month=ignored (help) - ↑ Wittesjö, B.; Björnham, A.; Eitrem, R. (1999). "Relative bradycardia in infectious diseases". J Infect. 39 (3): 246–7. PMID 10714809. Unknown parameter
|month=ignored (help)