Porokeratosis: Difference between revisions
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==Overview== | |||
Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the [[stratum corneum]] with a thin or absent granular layer.<ref name="Fitz2">Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.</ref> | |||
==Types== | ==Types== | ||
Porokeratosis may be divided into the following clinical types: | Porokeratosis may be divided into the following clinical types: | ||
:* [[Classic porokeratosis Mibelli]] | :* [[Classic porokeratosis Mibelli]] | ||
:* [[Disseminated superficial actinic porokeratosis]] | :* [[Disseminated superficial actinic porokeratosis]] | ||
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:* [[Punctate porokeratosis]] | :* [[Punctate porokeratosis]] | ||
However, additional types have also been described:<ref name="Andrews">James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. ISBN 0-7216-2921-0.</ref> | However, additional types have also been described:<ref name="Andrews">James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. ISBN 0-7216-2921-0.</ref> | ||
:* [[Porokeratosis plantaris discreta]] | :* [[Porokeratosis plantaris discreta]] | ||
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[[File:Porokeratosis - high mag.jpg|thumb|right|[[Micrograph]] of a case of porokeratosis showing a characteristic cornoid lamella (dark pink/red structure in the right/upper portion of the image). [[H&E stain]].]] | [[File:Porokeratosis - high mag.jpg|thumb|right|[[Micrograph]] of a case of porokeratosis showing a characteristic cornoid lamella (dark pink/red structure in the right/upper portion of the image). [[H&E stain]].]] | ||
Porokeratosis has a characteristic histomorphologic feature known as a ''cornoid lamella''. | Porokeratosis has a characteristic histomorphologic feature known as a ''cornoid lamella''. | ||
==References== | ==References== | ||
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Revision as of 17:32, 29 July 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer.[1]
Types
Porokeratosis may be divided into the following clinical types:
However, additional types have also been described:[2]
Pathology
Porokeratosis has a characteristic histomorphologic feature known as a cornoid lamella.