High anion gap metabolic acidosis critical pathways: Difference between revisions
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* Delta-Delta value is used to determine whether there is an additional metabolic acid-base disturbance or not. | * Delta-Delta value is used to determine whether there is an additional metabolic acid-base disturbance or not. | ||
* Delta-Delta (ΔΔ) = Delta anion gap (ΔAG) / Delta bicarbonate (ΔHCO3) | * Delta-Delta (ΔΔ) = Delta anion gap (ΔAG) / Delta bicarbonate (ΔHCO3) | ||
** Delta anion gap (ΔAG) = (Calculated anion gap - Expected anion gap) | |||
*** Calculated anion gap = [Na+] - [Cl-] - [HCO3-] | |||
*** Expected anion gap = 2.5 x serum albumin level | |||
** Delta bicarbonate (ΔHCO3) = 24 - serum bicarbonate level | |||
==References== | ==References== | ||
Revision as of 15:40, 1 August 2013
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Approach
| Metabolic acidosis physician extender algorithm |
| Elevated anion gap? | Yes | No |
| Delta-delta (ΔΔ) value | Equal to 1 | Greater than 1 | Less than 1 |
Definition
- Delta-Delta value is used to determine whether there is an additional metabolic acid-base disturbance or not.
- Delta-Delta (ΔΔ) = Delta anion gap (ΔAG) / Delta bicarbonate (ΔHCO3)
- Delta anion gap (ΔAG) = (Calculated anion gap - Expected anion gap)
- Calculated anion gap = [Na+] - [Cl-] - [HCO3-]
- Expected anion gap = 2.5 x serum albumin level
- Delta bicarbonate (ΔHCO3) = 24 - serum bicarbonate level
- Delta anion gap (ΔAG) = (Calculated anion gap - Expected anion gap)