Zieve's syndrome

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Zieve's syndrome is an acute metabolic condition that can occur during withdrawal from prolonged alcohol abuse. It is characterized by hemolytic anemia, hyperlipoproteineemia (excessive blood lipoprotein), jaundice, and abdominal pain. The underlying cause is liver delipidization. This is distinct from alcoholic hepatitis which, however, may present simultaneously or develop later.

Historical Perspective

Zieve's syndrome was initially described by Leslie Zieve in patients with a combination of alcoholic liver disease, hemolytic anemia and hypertriglyceridemia.

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