Leopard syndrome differential diagnosis: Difference between revisions
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==Overview== | |||
Cutaneous manifestations of LEOPARD syndrome may be similar to several other conditions including [[McCune-Albright syndrome]], [[Carney syndrome]], and [[neurofibromatosis]]. | |||
==Differentiating Leopard Syndrome From Other Diseases== | ==Differentiating Leopard Syndrome From Other Diseases== |
Revision as of 20:47, 6 September 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Cutaneous manifestations of LEOPARD syndrome may be similar to several other conditions including McCune-Albright syndrome, Carney syndrome, and neurofibromatosis.
Differentiating Leopard Syndrome From Other Diseases
It is suspected when two of the three following features are present:
- Endocrine(autonomous)hyperfunction such as precocious puberty,
- Fibrous dysplasia
- Café-au-lait spots
Within the syndrome there are bone fractures and deformity of the legs, arms and skull, different pigment patches on the skin, and early puberty with increased rate of growth.
coexistence of several neoplasms, including: gastric epithelioid leiomyosarcoma, pulmonary chondroma, and extra-adrenal paraganglioma