Leopard syndrome differential diagnosis: Difference between revisions
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==Differentiating Leopard Syndrome From Other Diseases== | ==Differentiating Leopard Syndrome From Other Diseases== | ||
* [[McCune-Albright syndrome]] | * [[McCune-Albright syndrome]] | ||
: | : The hallmark symptom of McCune-Albright syndrome is [[precocious puberty]]. Other symptoms include bone fractures, deformities of the bones in the face, gigantism, and irregular, large patchy [[café-au-lait spot]]s, especially on the back. | ||
*[[Carney syndrome]] | |||
: Coexistence of several neoplasms, including: gastric epithelioid leiomyosarcoma, pulmonary chondroma, and extra-adrenal paraganglioma | |||
*[[Lentigo]] | |||
*[[Neurofibromatosis]] | *[[Neurofibromatosis]] | ||
Revision as of 21:01, 6 September 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Cutaneous manifestations of LEOPARD syndrome may be similar to several other conditions including McCune-Albright syndrome, Carney syndrome, and neurofibromatosis. LEOPARD syndrome should also be distinguished from other syndromes with developmental delay, short stature, congenital heart defects, and distinctive facies, especially Williams syndrome.
Differentiating Leopard Syndrome From Other Diseases
- The hallmark symptom of McCune-Albright syndrome is precocious puberty. Other symptoms include bone fractures, deformities of the bones in the face, gigantism, and irregular, large patchy café-au-lait spots, especially on the back.
- Coexistence of several neoplasms, including: gastric epithelioid leiomyosarcoma, pulmonary chondroma, and extra-adrenal paraganglioma