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|Prompt=An experiment to measure the filtration fraction in healthy volunteers is conducted. One sample of the available urine and serum values is shown below. If the urine flow is 2.0 ml/min, what is the best approximate filtration fraction?
|Prompt=An experiment to measure the filtration fraction in healthy volunteers is conducted. One sample of the available urine and serum values is shown below. If the urine flow is 2.0 ml/min, what is the best approximate filtration fraction?


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{| class="wikitable" border="1" style="background:FloralWhite"
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| Variable|| Urine|| Serum
| Variable|| Urine|| Serum
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| PAH || 50 mg/ml || 0.2 mg/ml
| PAH || 50 mg/ml || 0.2 mg/ml
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|Explanation=Despite the presence of several parameters, utilization of only creatinine and PAH is required to calculate the filtration fraction.  
|Explanation=Despite the presence of several parameters, utilization of only creatinine and PAH is required to calculate the filtration fraction.  
Filtration fraction (FF) is calculated by the following equation: FF (%) = (GFR / RPF) x 100
Filtration fraction (FF) is calculated by the following equation: FF (%) = (GFR / RPF) x 100

Revision as of 01:41, 9 September 2013

 
Author [[PageAuthor::Rim Halaby, M.D. [1]]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Physiology
Sub Category SubCategory::Renal
Prompt [[Prompt::An experiment to measure the filtration fraction in healthy volunteers is conducted. One sample of the available urine and serum values is shown below. If the urine flow is 2.0 ml/min, what is the best approximate filtration fraction?


{]]

Answer A AnswerA::20$
Answer A Explanation AnswerAExp::According to the calculation, this is an incorrect answer.
Answer B AnswerB::30%
Answer B Explanation AnswerBExp::According to the calculation, this is an incorrect answer.
Answer C AnswerC::35%
Answer C Explanation AnswerCExp::According to the calculation, this is an incorrect answer.
Answer D AnswerD::40%
Answer D Explanation AnswerDExp::According to the calculation, this is a correct answer.
Answer E AnswerE::45%
Answer E Explanation AnswerEExp::According to the calculation, this is an incorrect answer.
Right Answer RightAnswer::D
Explanation [[Explanation::Despite the presence of several parameters, utilization of only creatinine and PAH is required to calculate the filtration fraction.

Filtration fraction (FF) is calculated by the following equation: FF (%) = (GFR / RPF) x 100

GFR = (UCr x V)/PCr = (100 x 2)/1 = 200 RPF = (UPAH x V)/PPAH = (50 x 2)/0.2 = 500 FF (%) = (GFR / RPF) x 100 = (200/500) x 100 = 0.4 x 100 = 40%


Educational Objective: FF (%) = (GFR/RPF) x 100
Educational Objective:
References: ]]

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