High chylomicron causes: Difference between revisions
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==Overview== | ==Overview== | ||
Most commonly hyperchylomicronemia is a result of deficient [[lipoprotein lipase enzyme]]. This deficiency could be genetic as in type I and type V [[hyperlipoprotenemia]]. Other conditions like [[alcoholism]], [[chronic renal failure]], [[hypothyroidism]] and [[diabetes mellitus]] can also affect the activity of [[lipoprotein lipase]] enzyme and can result in increased chylomicrons in blood. | |||
==Causes== | ==Causes== | ||
Revision as of 18:50, 17 September 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Most commonly hyperchylomicronemia is a result of deficient lipoprotein lipase enzyme. This deficiency could be genetic as in type I and type V hyperlipoprotenemia. Other conditions like alcoholism, chronic renal failure, hypothyroidism and diabetes mellitus can also affect the activity of lipoprotein lipase enzyme and can result in increased chylomicrons in blood.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Heparin, oral contraceptive, thiazide |
| Ear Nose Throat | No underlying causes |
| Endocrine | Diabetes mellitus |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | Glycogen storage disease type I, lipoprotein lipase deficiency , type 1C hyperlipoproteinemia, mixed hyperlipoproteinemia |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | Familial hypertriglyceridemia, glycogen storage disease type I, lipoprotein lipase deficiency |
| Obstetric/Gynecologic | Pregnancy |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | Alcohol |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | Chronic renal failure |
| Rheumatology/Immunology/Allergy | Autoimmune hyperchylomicronemia |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |