High chylomicron causes: Difference between revisions
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==Overview== | ==Overview== | ||
Hyperchylomicronemia occurs more commonly as a result of deficient [[lipoprotein lipase enzyme]]. This deficiency could either be [[genetic]] as in [[Hyperlipoproteinemia|type I and type V hyperlipoproteinemia]] or due to conditions such as [[alcoholism]], [[chronic renal failure]], [[hypothyroidism]], and [[diabetes mellitus]] which | Hyperchylomicronemia occurs more commonly as a result of deficient [[lipoprotein lipase enzyme]]. This deficiency could either be [[genetic]] as in [[Hyperlipoproteinemia|type I and type V hyperlipoproteinemia]] or due to conditions such as [[alcoholism]], [[chronic renal failure]], [[hypothyroidism]], and [[diabetes mellitus]] which lower the activity of [[lipoprotein lipase]] enzyme. | ||
==Causes== | ==Causes== | ||
Revision as of 19:21, 17 September 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Hyperchylomicronemia occurs more commonly as a result of deficient lipoprotein lipase enzyme. This deficiency could either be genetic as in type I and type V hyperlipoproteinemia or due to conditions such as alcoholism, chronic renal failure, hypothyroidism, and diabetes mellitus which lower the activity of lipoprotein lipase enzyme.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Hyperchylomicronemia in itself is not a life-threatening condition.
Common Causes
- Alcohol
- Chronic renal failure
- Diabetes mellitus
- Hypothyroidism
- Oral contraceptives
- Pregnancy
- Thiazide diuretics
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Heparin, oral contraceptives, thiazide diuretics |
| Ear Nose Throat | No underlying causes |
| Endocrine | Diabetes mellitus, hypothyroidism |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | Glycogen storage disease type I, lipoprotein lipase deficiency , type 1C hyperlipoproteinemia, mixed hyperlipoproteinemia |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | Familial hypertriglyceridemia, glycogen storage disease type I, lipoprotein lipase deficiency |
| Obstetric/Gynecologic | Pregnancy |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | Alcohol |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | Chronic renal failure |
| Rheumatology/Immunology/Allergy | Autoimmune hyperchylomicronemia |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |