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==Definition==
==Definition==

Revision as of 16:58, 18 September 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ;Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Definition

Many large studies and clinical trials have been done to prove the inverse relation between HDL and the risk of cardiovascular diseases,[1][2] and the fact that more increase in HDL level improves the cardiovascular health.[3] The serum HDL level Goals for Patients at Risk of cardiovascular disease is recommended to be as high as possible, but at least ≥40 mg/dL in both men and women. Many debate about the serum level at which the risk of cardiovascular disease occurrence decline, an HDL value of ≥60 mg/dL is considered protective against heart disease according to latest guidelines.

Guideline Resource

https://www.aace.com/files/lipid-guidelines.pdf

References

  1. Gotto AM, Whitney E, Stein EA, Shapiro DR, Clearfield M, Weis S; et al. (2000). "Relation between baseline and on-treatment lipid parameters and first acute major coronary events in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS)". Circulation. 101 (5): 477–84. PMID 10662743.
  2. Emerging Risk Factors Collaboration. Di Angelantonio E, Sarwar N, Perry P, Kaptoge S, Ray KK; et al. (2009). "Major lipids, apolipoproteins, and risk of vascular disease". JAMA. 302 (18): 1993–2000. doi:10.1001/jama.2009.1619. PMC 3284229. PMID 19903920. Review in: Ann Intern Med. 2010 Feb 16;152(4):JC-212
  3. Sirtori, Cesare R. (October 2006). "HDL and the progression of atherosclerosis: new insights". European Heart Journal Supplements.


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