High cholesterol causes: Difference between revisions

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{{col-begin|width=80%}}
{{col-begin|width=80%}}
{{col-break|width=33%}}
{{col-break|width=33%}}
*[[Apo A-I deficiency]]
*[Apo A-I deficiency]]
*[[Berardinelli–Seip syndrome]]
*[[Berardinelli–seip syndrome ]]
*[[Diabetes mellitus]]
*[[Diabetes mellitus]]
*[[Alcoholism]]
*[[Hypothyroidism]]
*[[Hypothyroidism]]
*[[IgA nephropathy ]]
*[[Hashimoto's thyroiditis ]]
*[[Hashimoto's thyroiditis ]]
*[[Metabolic syndrome ]]
*[[Metabolic syndrome ]]
Line 26: Line 24:
*[[Apolipoprotein C2|Apolipoprotein C2 deficiency]]
*[[Apolipoprotein C2|Apolipoprotein C2 deficiency]]
*[[Apolipoprotein E|Apoliprotein E deficiency]]
*[[Apolipoprotein E|Apoliprotein E deficiency]]
*[[Familial hypercholesterolemia|Autosomal recessive hypercholesterolemia]]
*[[Autosomal recessive hypercholesterolemia]]
*[[Beta blockers]]
*[[Beta blockers]]
{{col-break|width=33%}}
{{col-break|width=33%}}
*[[Binge eating disorder]]
*[[Binge eating disorder]]
*[[Chronic kidney disease]]
*[[Chronic kidney disease]]
*[[Corticosteroids]]  
*[[Corticosteroids]]
*[[Cyclosporine]]
*[[Cyclosporine]]
*[[Estrogens]]
*[[Estrogens]]
*[[Everolimus]]  
*[[Everolimus]]
*[[Familial combined hyperlipidemia]]
*[[Familial combined hyperlipidemia]]
*[[Familial hypercholesterolemia]]
*[[Familial hypercholesterolemia]]
*[[Fosamprenavir]]
*[[Glycogen storage disease type 1a]]
*[[Glycogen storage disease type 1a]]
*[[Glycogenosis type 3]]
*[[Glycogenosis type 3]]
*[[Glycogenosis type 6]]
*[[Glycogenosis type 6]]
*[[Hyperlipoproteinemia|Familial hyperlipoproteinemia type 5]]
*[[Hyperlipoproteinemia|Familial hyperlipoproteinemia type 5]]
*[[Hypothyroidism]]
*[[Hypothyroidism]]
*[[Lack of physical inactivity ]]
*[[Lecithin cholesterol acyltransferase deficiency]]
*[[Lecithin cholesterol acyltransferase deficiency]]
*[[Lipoprotein lipase deficiency]]
*[[Mitotane]]
{{col-break|width=33%}}
{{col-break|width=33%}}
*[[Lipoprotein lipase deficiency]]
*[[Nephrotic syndrome]]
*[[Nephrotic syndrome]]
*[[Niemann-Pick disease type B]]
*[[Niemann-Pick disease, type B ]]
*[[Obesity]]  
*[[Obesity]]
*[[Olanzapine]]
*[[Olanzapine]]
*[[Polycystic ovary syndrome]]
*[[Polycystic ovary syndrome]]
Line 55: Line 52:
*[[Primary biliary cirrhosis]]
*[[Primary biliary cirrhosis]]
*[[Sirolimus]]
*[[Sirolimus]]
*[[Stauffer syndrome]]
*[[Tamoxifen ]]
*[[Temsirolimus]]
*[[Temsirolimus]]
*[[Thiazide diuretics]]
*[[Thiazide diuretics ]]
*[[Tocilizumab]]
*[[Tofacitinib]]
*[[Tofacitinib]]
*[[Werner syndrome]]
*[[Zieve's syndrome]]
*[[Zieve's syndrome]]
{{col-end}}
{{col-end}}
Line 84: Line 77:
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Antiretroviral therapy]], [[beta blockers]], [[corticosteroids]], [[cyclosporine]], [[estrogens]], [[everolimus]], [[fosamprenavir]], [[mitotane]], [[olanzapine]], [[sirolimus]], [[tamoxifen ]], [[temsirolimus]], [[thiazide diuretics]], [[tocilizumab]], [[tofacitinib]]
|bgcolor="Beige"| [[Cyclosporine]], [[estrogens]], [[everolimus]], [[olanzapine]], [[sirolimus]], [[temsirolimus]], [[thiazide diuretics ]], [[tofacitinib]]  
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"| [[Metabolic syndrome]], [[polycystic ovary syndrome]], [[Werner syndrome]]
|bgcolor="Beige"| [[Diabetes mellitus]], [[metabolic syndrome]], [[polycystic ovary syndrome]],[[hypothyroidism]],
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| '''Gastroenterologic'''
|bgcolor="Beige"| [[Glycogenosis type 6]], [[Niemann-Pick disease type B ]], [[primary biliary cirrhosis]], [[Stauffer syndrome]], [[Zieve's syndrome]]
|bgcolor="Beige"| [[Glycogenosis type 3]], [[glycogenosis type 6]], [[Niemann-Pick disease type B ]], [[primary biliary cirrhosis]], [[Stauffer syndrome]], [[Zieve's syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| [[Apo A-I deficiency]], [[apolipoprotein B deficiency]], [[apolipoprotein c2|apolipoprotein C2 deficiency]], [[apoliprotein e|apoliprotein e deficiency]], [[familial hypercholesterolemia|autosomal recessive hypercholesterolemia]], [[familial combined hyperlipidemia]], [[familial hypercholesterolemia]], [[glycogen storage disease type 1a]], [[glycogenosis type 3]], [[glycogenosis type 6]], [[hyperlipoproteinemia|familial hyperlipoproteinemia type 5]], [[lecithin cholesterol acyltransferase deficiency]], [[lipoprotein lipase deficiency]], [[Niemann-Pick disease type B]], [[Werner syndrome]]
|bgcolor="Beige"| [[Analbuminaemia]], [[apo A-I deficiency]], [[apolipoprotein B deficiency]], [[apolipoprotein c2|apolipoprotein C2 deficiency]], [[apoliprotein e|apoliprotein E deficiency]], [[familial hypercholesterolemia|autosomal recessive hypercholesterolemia]], [[familial combined hyperlipidemia]], [[familial hypercholesterolemia]], [[glycogen storage disease type 1a]], [[glycogenosis type 3]], [[glycogenosis type 6]], [[hyperlipoproteinemia|familial hyperlipoproteinemia type 5]], [[lecithin cholesterol acyltransferase deficiency]], [[lipoprotein lipase deficiency]], [[Niemann-Pick disease type B]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[ Berardinelli–Seip syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Apo A-I deficiency]], [[apoliprotein E deficiency]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
| '''Nutritional/Metabolic'''
|bgcolor="Beige"|[[Metabolic syndrome]], [[ Niemann-Pick disease type B]], [[obesity]], [[Zieve's syndrome]]
|bgcolor="Beige"|[[Metabolic syndrome]], [[ Niemann-Pick disease type B]], [[obesity]], [[Zieve's syndrome]],[[Berardinelli–seip syndrome]], [[analbuminaemia]], [[diabetes mellitus]], [[diabetes mellitus]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Polycystic ovary syndrome]], [[pregnancy]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
| '''Ophthalmologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Alström syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Binge eating disorder]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
| '''Renal/Electrolyte'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Chronic kidney disease]], [[nephrotic syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[hashimoto's thyroiditis ]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Lack of physical inactivity ]]|-
|-
|}
|}


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{{col-break|width=33%}}
{{col-break|width=33%}}
*[[Apo A-I deficiency]]
*[Apo A-I deficiency]]
*[[Familial hypercholesterolemia|Autosomal recessive hypercholesterolemia]]
*[[Alagille syndrome]]
*[[Alagille syndrome]]
*[[Alström syndrome]]
*[[Alström syndrome]]
Line 192: Line 183:
*[[Apolipoprotein C2|Apolipoprotein C2 deficiency]]
*[[Apolipoprotein C2|Apolipoprotein C2 deficiency]]
*[[Apolipoprotein E|Apoliprotein E deficiency]]
*[[Apolipoprotein E|Apoliprotein E deficiency]]
*[[Alcoholism]]
*[[Autosomal recessive hypercholesterolemia]]
*[[Beta blockers]]
*[[Beta blockers]]
*[[Binge eating disorder]]
*[[Binge eating disorder]]
*[[Berardinelli–Seip syndrome]]
*[[Berardinelli–seip syndrome ]]
*[[Chronic kidney disease]]
*[[Chronic kidney disease]]
*[[Corticosteroids]]
*[[Corticosteroids]]
*[[Cyclosporine]]
*[[Cyclosporine]]
{{col-break|width=33%}}
*[[Diabetes mellitus]]
*[[Diabetes mellitus]]
{{col-break|width=33%}}
*[[Estrogens]]
*[[Estrogens]]
*[[Everolimus]]
*[[Everolimus]]
*[[Familial combined hyperlipidemia]]
*[[Familial combined hyperlipidemia]]
*[[Familial hypercholesterolemia]]
*[[Familial hypercholesterolemia]]
*[[Glycogen storage disease type 1a]]
*[[Glycogenosis type 3]]
*[[Glycogenosis type 6]]
*[[Hypothyroidism]]
*[[Hyperlipoproteinemia|Familial hyperlipoproteinemia type 5]]
*[[Hyperlipoproteinemia|Familial hyperlipoproteinemia type 5]]
*[[Fosamprenavir]]
*[[Glycogen storage disease  type 1a]]
*[[Glycogenosis type 3]]
*[[Glycogenosis type 6]]
*[[Hypothyroidism]]
*[[Hypothyroidism]]
*[[Hashimoto's thyroiditis ]]
*[[Hashimoto's thyroiditis ]]
*[[IgA nephropathy ]]
*[[Lack of physical inactivity ]]
*[[Lecithin cholesterol acyltransferase deficiency]]
*[[Lecithin cholesterol acyltransferase deficiency]]
{{col-break|width=33%}}
*[[Lipoprotein lipase deficiency]]
*[[Lipoprotein lipase deficiency]]
*[[Mitotane]]
*[[Metabolic syndrome ]]
*[[Metabolic syndrome ]]
{{col-break|width=33%}}
*[[Nephrotic syndrome]]
*[[Nephrotic syndrome]]
*[[Niemann-Pick disease type B]]
*[[Niemann-Pick disease, type B ]]
*[[Obesity]]
*[[Obesity]]
*[[Olanzapine]]
*[[Olanzapine]]
Line 226: Line 216:
*[[Primary biliary cirrhosis]]
*[[Primary biliary cirrhosis]]
*[[Sirolimus]]
*[[Sirolimus]]
*[[Stauffer syndrome]]
*[[Tamoxifen ]]
*[[Temsirolimus]]
*[[Temsirolimus]]
*[[Thiazide diuretics]]
*[[Thiazide diuretics ]]
*[[Tocilizumab]]
*[[Tofacitinib]]
*[[Tofacitinib]]
*[[Werner syndrome]]
*[[Zieve's syndrome]]
*[[Zieve's syndrome]]
{{col-end}}
{{col-end}}

Revision as of 19:44, 19 September 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Overview

High cholesterol level can result from various causes which include: genetic (e.g. apo A-I deficiency, apolipoprotein B deficiency, apolipoprotein C2 deficiency, apoliprotein E deficiency, autosomal recessive hypercholesterolemia, familial combined hyperlipidemia, familial hypercholesterolemia); side effect of medications (e.g. antiretroviral therapy, beta blockers, corticosteroids); metabolic (e.g. metabolic syndrome, Niemann-Pick disease type B, obesity, Zieve's syndrome), endocrine (e.g. polycystic ovary syndrome, Werner syndrome) and many other conditions.

Causes

Common Causes

Causes by Organ System

Cardiovascular Alagille syndrome, familial hypercholesterolemia
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect Cyclosporine, estrogens, everolimus, olanzapine, sirolimus, temsirolimus, thiazide diuretics , tofacitinib
Ear Nose Throat No underlying causes
Endocrine Diabetes mellitus, metabolic syndrome, polycystic ovary syndrome,hypothyroidism,
Environmental No underlying causes
Gastroenterologic Glycogenosis type 3, glycogenosis type 6, Niemann-Pick disease type B , primary biliary cirrhosis, Stauffer syndrome, Zieve's syndrome
Genetic Analbuminaemia, apo A-I deficiency, apolipoprotein B deficiency, apolipoprotein C2 deficiency, apoliprotein E deficiency, autosomal recessive hypercholesterolemia, familial combined hyperlipidemia, familial hypercholesterolemia, glycogen storage disease type 1a, glycogenosis type 3, glycogenosis type 6, familial hyperlipoproteinemia type 5, lecithin cholesterol acyltransferase deficiency, lipoprotein lipase deficiency, Niemann-Pick disease type B
Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease No underlying causes
Musculoskeletal/Orthopedic Berardinelli–Seip syndrome
Neurologic Apo A-I deficiency, apoliprotein E deficiency
Nutritional/Metabolic Metabolic syndrome, Niemann-Pick disease type B, obesity, Zieve's syndrome,Berardinelli–seip syndrome, analbuminaemia, diabetes mellitus, diabetes mellitus
Obstetric/Gynecologic Polycystic ovary syndrome, pregnancy
Oncologic No underlying causes
Ophthalmologic Alström syndrome
Overdose/Toxicity No underlying causes
Psychiatric Binge eating disorder
Pulmonary No underlying causes
Renal/Electrolyte Chronic kidney disease, nephrotic syndrome
Rheumatology/Immunology/Allergy hashimoto's thyroiditis
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous Lack of physical inactivity |-

Causes in Alphabetical Order

References


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