|
|
| Line 4: |
Line 4: |
|
| |
|
| ==Overview== | | ==Overview== |
| High cholesterol level can be caused by a wide variety of factors. Genetic, endocrine, and metabolic factors are the major participants in the development of high cholesterol level. Examples of common causes include [[diabetes mellitus]], [[familial hypercholesterolemia]], drug side effects, and kidney disease.
| | Elevated cholesterol level can be caused by a wide variety of factors. Genetic, endocrine, and metabolic factors are the major participants in the development of high cholesterol level. Examples of common causes include [[diabetes mellitus]], [[familial hypercholesterolemia]], drug side effects, and kidney disease. |
|
| |
|
| ==Causes== | | ==Causes== |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Elevated cholesterol level can be caused by a wide variety of factors. Genetic, endocrine, and metabolic factors are the major participants in the development of high cholesterol level. Examples of common causes include diabetes mellitus, familial hypercholesterolemia, drug side effects, and kidney disease.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
High cholesterol in itself is not a life threatening condition.
Common Causes
Causes by Organ System
| Cardiovascular
|
Alagille syndrome, familial hypercholesterolemia
|
| Chemical/Poisoning
|
No underlying causes
|
| Dental
|
No underlying causes
|
| Dermatologic
|
No underlying causes
|
| Drug Side Effect
|
Cyclosporine, estrogens, everolimus, olanzapine, sirolimus, temsirolimus, thiazide diuretics , tofacitinib
|
| Ear Nose Throat
|
No underlying causes
|
| Endocrine
|
Diabetes mellitus, metabolic syndrome, polycystic ovary syndrome,hypothyroidism
|
| Environmental
|
No underlying causes
|
| Gastroenterologic
|
Glycogenosis type 3, glycogenosis type 6, Niemann-Pick disease type B , primary biliary cirrhosis, Stauffer syndrome, Zieve's syndrome
|
| Genetic
|
Analbuminaemia, apo A-I deficiency, apolipoprotein B deficiency, Apolipoprotein C2 deficiency, apoliprotein E deficiency, autosomal recessive hypercholesterolemia, familial combined hyperlipidemia, familial hypercholesterolemia, glycogen storage disease type 1a, glycogenosis type 3, glycogenosis type 6, familial hyperlipoproteinemia type 5, lecithin cholesterol acyltransferase deficiency, lipoprotein lipase deficiency, Niemann-Pick disease type B
|
| Hematologic
|
Zieve's syndrome
|
| Iatrogenic
|
No underlying causes
|
| Infectious Disease
|
No underlying causes
|
| Musculoskeletal/Orthopedic
|
Berardinelli–Seip syndrome
|
| Neurologic
|
Apo A-I deficiency, apoliprotein E deficiency
|
| Nutritional/Metabolic
|
Metabolic syndrome, Niemann-Pick disease type B, obesity, Zieve's syndrome,Berardinelli–Seip syndrome, analbuminaemia, diabetes mellitus, Glycogenosis type 3, glycogenosis type 6
|
| Obstetric/Gynecologic
|
Polycystic ovary syndrome, pregnancy
|
| Oncologic
|
No underlying causes
|
| Ophthalmologic
|
Alström syndrome
|
| Overdose/Toxicity
|
No underlying causes
|
| Psychiatric
|
Binge eating disorder
|
| Pulmonary
|
No underlying causes
|
| Renal/Electrolyte
|
Chronic kidney disease, nephrotic syndrome
|
| Rheumatology/Immunology/Allergy
|
hashimoto's thyroiditis
|
| Sexual
|
No underlying causes
|
| Trauma
|
No underlying causes
|
| Urologic
|
No underlying causes
|
| Miscellaneous
|
Lack of physical inactivity
|
Causes in Alphabetical Order
References
Template:WikiDoc Sources