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==Definition==
==Definition==
Low HDL-cholesterol cut-off value has been recently subject to variable changes.  In the Pan-European survey of HDL-cholesterol set out to determine the prevalence of low HDL-cholesterol, low HDL cut-off values were defined as 1.03 mmol/L (40 mg/dL) and 1.29 mmol/L (50 mg/dL) in men and women respectively.<ref>{{Cite web  | last =  | first =  | title = Defining the prevalence of low HDL-C in a European cohort of dyslipidaemic patients | url = http://eurheartjsupp.oxfordjournals.org/content/7/suppl_F/F23.full?sid=70412a9e-1bf7-486e-90a9-0ae32b4ad6b1 | publisher =  | date =  | accessdate = 20 September 2013 }} </ref>  However, based on the risk of cardiovascular disease at levels above 35 mg/dL, the [[Adult Treatment Panel guidelines (ATP III)]] panel recognized a higher cut-off value for low HDL levels that is <40 mg/dL in both men and women.  It is to be noted that the cut-off value for low HDL is the same for both genders since the use of gender specific cut-point value might cause many low risk women to be eligible for LDL-lowering medications.<ref name="pmid12485966">{{cite journal| author=National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)| title=Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. | journal=Circulation | year= 2002 | volume= 106 | issue= 25 | pages= 3143-421 | pmid=12485966 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12485966  }} </ref>
Low HDL-cholesterol cut-off value has been recently subject to variable changes.  In the Pan-European survey of HDL-cholesterol set out to determine the prevalence of low HDL-cholesterol, low HDL cut-off values were defined as 1.03 mmol/L (40 mg/dL) and 1.29 mmol/L (50 mg/dL) in men and women respectively.<ref>{{Cite web  | last =  | first =  | title = Defining the prevalence of low HDL-C in a European cohort of dyslipidaemic patients | url = http://eurheartjsupp.oxfordjournals.org/content/7/suppl_F/F23.full?sid=70412a9e-1bf7-486e-90a9-0ae32b4ad6b1 | publisher =  | date =  | accessdate = 20 September 2013 }} </ref>  However, based on the risk of cardiovascular disease at levels below 35 mg/dL, the [[Adult Treatment Panel guidelines (ATP III)]] panel recognized a higher cut-off value for low HDL levels that is <40 mg/dL in both men and women.  It is to be noted that the cut-off value for low HDL is the same for both genders since the use of gender specific cut-point value might cause many low risk women to be eligible for LDL-lowering medications.<ref name="pmid12485966">{{cite journal| author=National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)| title=Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. | journal=Circulation | year= 2002 | volume= 106 | issue= 25 | pages= 3143-421 | pmid=12485966 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12485966  }} </ref>


==References==
==References==

Revision as of 21:52, 9 October 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Overview

Low HDL level cut-off point has been a debate in many surveys. Most recently, it was set to be below 1.0 mmol/L (40 mg/dL) in both men and women.[1]

Definition

Low HDL-cholesterol cut-off value has been recently subject to variable changes. In the Pan-European survey of HDL-cholesterol set out to determine the prevalence of low HDL-cholesterol, low HDL cut-off values were defined as 1.03 mmol/L (40 mg/dL) and 1.29 mmol/L (50 mg/dL) in men and women respectively.[2] However, based on the risk of cardiovascular disease at levels below 35 mg/dL, the Adult Treatment Panel guidelines (ATP III) panel recognized a higher cut-off value for low HDL levels that is <40 mg/dL in both men and women. It is to be noted that the cut-off value for low HDL is the same for both genders since the use of gender specific cut-point value might cause many low risk women to be eligible for LDL-lowering medications.[1]

References

  1. 1.0 1.1 National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) (2002). "Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report". Circulation. 106 (25): 3143–421. PMID 12485966.
  2. "Defining the prevalence of low HDL-C in a European cohort of dyslipidaemic patients". Retrieved 20 September 2013.


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