WBR0641

Author	[[PageAuthor::Rim Halaby, M.D. [1]]]
Exam Type	ExamType::USMLE Step 1
Main Category	MainCategory::Immunology
Sub Category	SubCategory::Hematology
Prompt	[[Prompt::A 7 month old boy is brought to the emergency room for bloody diarrhea. The mother explains that she had been noticing blood tinged stools for the past week; but today, she notes frank blood in the diapers. On admission, the child appears well, his pulse is 123 bpm and his temperature is 36.8 degrees C (98.24 degrees F). Physical examination reveals multiple petechiae in the oral cavity. Skin inspection shows purpura most prominent on the legs and patchy eczema affecting the limbs, face, and trunk. Upon further questioning, the mother reports that the child has a history of multiple hospital admissions for recurrent respiratory tract infections. Which of the following best describes the pathophysiology of the disease most likely present in this patient?]]
Answer A	AnswerA::Defect in DNA repair enzymes
Answer A Explanation	AnswerAExp::
Answer B	AnswerB::T-cell inability to reorganize cytoskeleton
Answer B Explanation	AnswerBExp::
Answer C	AnswerC::Defect in lysosomal trafficking
Answer C Explanation	AnswerCExp::
Answer D	AnswerD::Defect in Th1 response
Answer D Explanation	AnswerDExp::
Answer E	AnswerE::Defect in CD18 protein on phagocytes
Answer E Explanation	AnswerEExp::
Right Answer	RightAnswer::B
Explanation	[[Explanation:: Educational Objective: References: ]]
Approved	Approved::No
Keyword
Linked Question	Linked::
Order in Linked Questions	LinkedOrder::