Low LDL causes: Difference between revisions

	Low Density Lipoprotein Microchapters
Home
Patient information
Overview
Historical Perspective
Classification
Physiology
Pathophysiology
Causes Low LDL High LDL
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Prognosis and Complications
Diagnosis
Laboratory Findings
Treatment
Medical Therapy
Landmark Trials
Future or Investigational Therapies
Case Studies
Case #1
Low LDL causes On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Low LDL causes All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Low LDL causes
CDC on Low LDL causes
Low LDL causes in the news
Blogs on Low LDL causes
Directions to Hospitals Treating Low density lipoprotein
Risk calculators and risk factors for Low LDL causes

VisualWikitext

Revision as of 18:53, 20 November 2013

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Rim Halaby, M.D. [3]; Vendhan Ramanujam M.B.B.S [4]

Overview

Low LDL levels can be caused by unusual inherited disorders of lipoprotein metabolism such as abetalipoproteinemia and hypobetalipoproteinemia.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Low LDL does not have any life-threatening cause.

Common Causes

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	Dyskeratosis congenita, lipomatosis of Madelung
Drug Side Effect	Clofibrate, colesevelam hydrochlorie, colestyramine, doxazosin, nicotinic acid, NSAID, prazosin, probucol, statins
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	Ketogenic diet, malnutrition
Gastroenterologic	Celiac disease, chronic liver disease, chronic pancreatitis, cirrhosis, Crohn's disease, exocrine pancreatic insufficiency, intestinal lymphangiectasia, liver failure, portosystemic shunts, protein losing enteropathy, short bowel syndrome
Genetic	Abetalipoproteinemia, apolipoprotein B deficiency, Bassen-Kornzweig disease, cystic fibrosis, deficiency of proprotein convertase subtilisin-like/kexin type 9, dyskeratosis congenita, familial alphalipoprotein deficiency, familial hypobetalipoproteinemia, familial type 5 hyperlipoproteinemia, hypobetalipoproteinemia, lipoprotein lipase deficiency, mutations of the MTTP gene, Shwachman-Diamond syndrome
Hematologic	Acute myeloid leukemia
Iatrogenic	Portosystemic shunts, short bowel syndrome
Infectious Disease	Giardiasis
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	Abetalipoproteinemia, apolipoprotein B deficiency, Bassen-Kornzweig disease, familial alphalipoprotein deficiency, familial hypobetalipoproteinemia, familial type 5 hyperlipoproteinemia, hypobetalipoproteinemia, lipoprotein lipase deficiency, mutations of the MTTP gene
Obstetric/Gynecologic	No underlying causes
Oncologic	Acute myeloid leukemia, malignancy
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Acute phase proteins, amyloidosis, autoimmune diseases, celiac disease, inflammatory cytokines, high serum amyloid A, Sjögren's syndrome
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

References

↑ Scanu, AM.; Aggerbeck, LP.; Kruski, AW.; Lim, CT.; Kayden, HJ. (1974). "A study of the abnormal lipoproteins in abetalipoproteinemia". J Clin Invest. 53 (2): 440–53. doi:10.1172/JCI107578. PMID 11344558. Unknown parameter |month= ignored (help)
↑ Welty, FK.; Mittleman, MA.; Wilson, PW.; Sutherland, PA.; Matheney, TH.; Lipinska, I.; Muller, JE.; Levy, D.; Tofler, GH. (1997). "Hypobetalipoproteinemia is associated with low levels of hemostatic risk factors in the Framingham offspring population". Circulation. 95 (4): 825–30. PMID 9054738. Unknown parameter |month= ignored (help)

Template:WikiDoc Sources

[Scanu-1974-1] Scanu, AM.; Aggerbeck, LP.; Kruski, AW.; Lim, CT.; Kayden, HJ. (1974). "A study of the abnormal lipoproteins in abetalipoproteinemia". J Clin Invest. 53 (2): 440–53. doi:10.1172/JCI107578. PMID 11344558. Unknown parameter |month= ignored (help)

[Welty-1997-2] Welty, FK.; Mittleman, MA.; Wilson, PW.; Sutherland, PA.; Matheney, TH.; Lipinska, I.; Muller, JE.; Levy, D.; Tofler, GH. (1997). "Hypobetalipoproteinemia is associated with low levels of hemostatic risk factors in the Framingham offspring population". Circulation. 95 (4): 825–30. PMID 9054738. Unknown parameter |month= ignored (help)

[1]

[2]

@@ Line 111: / Line 111: @@
 |-bgcolor="LightSteelBlue"
 | '''Rheumatology/Immunology/Allergy'''
-|bgcolor="Beige"| [[Acute phase proteins]], [[amyloidosis]], [[autoimmune diseases]], [[celiac disease]], [[Cytokine|inflammatory cytokines]], [[serum amyloid A]], [[Sjögren's syndrome]]
+|bgcolor="Beige"| [[Acute phase proteins]], [[amyloidosis]], [[autoimmune diseases]], [[celiac disease]], [[Cytokine|inflammatory cytokines]], [[serum amyloid A|high serum amyloid A]], [[Sjögren's syndrome]]
 |-
 |-bgcolor="LightSteelBlue"

v t e Lipopedia
Basic Science	Cholesterol • Triglyceride Lipoprotein metabolism and transport Lipoprotein: Chylomicron • Chylomicron remnant • HDL • IDL • LDL • Lipoprotein(a) • VLDL • Lipoprotein-X Apolipoprotein: APOA (1, 2, 4, 5) • APOB ( Apolipoprotein B-48, Apolipoprotein B-100) • APOC (1, 2, 3, 4) • APOD • APOE • APOH • APOJ • APOL • APOM • Apo(a) Lipoprotein receptor: LDL receptor • Soluble low density lipoprotein receptor-related protein (sLRP) • Apolipoprotein E Receptor 2 • Scavenger receptor • Scavenger receptor A • Scavenger receptor B • VLDL receptor Lipoprotein enzymes: Lipoprotein lipase • Lipoprotein-associated phospholipase A2 (Lp-PLA2) • Cholesterylester transfer protein ( Acetyl-CoA C-acyltransferase, Lecithin-cholesterol acyltransferase) • Microsomal triglyceride transfer protein • ABCA1 Genes: Low density lipoprotein receptor gene family • Microsomal triglyceride transfer protein • ABCA1
Lipoprotein Disorders	Lipoprotein disorders Primary lipoprotein disorders: Familial hyperchylomicronemia (Type I) • Familial hypercholesterolemia (Type IIA) • Familial combined hyperlipidemia (Type IIB) • Dysbetalipoproteinemia (Type III) • Primary hypertriglyceridemia (Type IV) • Mixed hyperlipoproteinemia (Type V) Secondary lipoprotein disorders
Abnormal Laboratory Lipid Profile	Low chylomicron • Low chylomicron remnant • Low HDL • Low IDL • Low LDL • Low lipoprotein(a) • Low VLDL High chylomicron • High chylomicron remnant • High HDL • High IDL • High LDL • High Lipoprotein(a) • High VLDL