Ventricular remodeling overview: Difference between revisions
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==Overview== | ==Overview== | ||
'''Ventricular remodeling''' refers to the changes in size, shape, and function of the heart after injury to the [[left ventricle]]. The injury is typically due to [[acute myocardial infarction]] (usually transmural or ST segment elevation infarction), but may be from a number of causes that result in increased pressure or volume overload (forms of strain) on the heart. Chronic [[hypertension]], [[congenital heart disease]] with intracardiac shunting, and [[valvular heart disease]] may also lead to remodeling. After the insult occurs, a series of histopathological and structural changes occur in the left ventricular myocardium that lead to progressive decline in left ventricular performance. Ultimately, ventricular remodeling may result in diminished contractile ([[systolic]]) function and reduced [[stroke volume]]. | |||
Medically speaking, "ventricular remodeling" implies a decline in function (even though the word "remodeling" usually implies improvement). The term "reverse remodeling" in cardiology implies an improvement in ventricular mechanics and function after a remote injury. | |||
==Classification== | ==Classification== | ||
Revision as of 17:54, 26 November 2013
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Ventricular Remodeling |
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Differentiating Ventricular Remodeling From Other Conditions |
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Diagnosis |
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Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Ventricular remodeling refers to the changes in size, shape, and function of the heart after injury to the left ventricle. The injury is typically due to acute myocardial infarction (usually transmural or ST segment elevation infarction), but may be from a number of causes that result in increased pressure or volume overload (forms of strain) on the heart. Chronic hypertension, congenital heart disease with intracardiac shunting, and valvular heart disease may also lead to remodeling. After the insult occurs, a series of histopathological and structural changes occur in the left ventricular myocardium that lead to progressive decline in left ventricular performance. Ultimately, ventricular remodeling may result in diminished contractile (systolic) function and reduced stroke volume.
Medically speaking, "ventricular remodeling" implies a decline in function (even though the word "remodeling" usually implies improvement). The term "reverse remodeling" in cardiology implies an improvement in ventricular mechanics and function after a remote injury.