Vasopressor resident survival guide

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]

Management

Vasopressors

Norepinephrine

Dopamine

Vasopressin

Phenylephrine

Dobutamine

Mechanism of action

Mainly α1( Vasoconstrictive ) β1( ↑contractility )

Mainly β1( ↑contractility ) α1( Vasoconstrictive )

V1 receptor of GIT smooth muscle Antidiuretic effects

Pure α1( Vasoconstrictive ) No β1

Mainly β1 ( ↑contractility ) β2 smooth muscles of vasculature ( Hypotensive )

Indication

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Dose

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Complications

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Cautions

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Do's

• Assess the cause of shock
• Always volume fluid resuscitation first
• Norepinephrine in undifferentiated shock.