Vasopressor resident survival guide

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]

Management

Vasopressors

Norepinephrine

Dopamine

Vasopressin

Phenylephrine

Dobutamine

Mechanism of action

*Mainly α1 (Vasoconstrictive) *β1 (↑contractility)

*Mainly β1(↑contractility) *α1(Vasoconstrictive)

*V1 receptor of GIT vasculatures *Antidiuretic effects

*Pure α1 (Vasoconstrictive) *No β1

*Mainly β1 (↑contractility) *β2 arterial smooth muscle (Hypotensive)

Indication

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Dose

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Complications

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Cautions

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Do's

• Assess the cause of shock
• Always volume fluid resuscitation first
• Norepinephrine in undifferentiated shock.