Vasopressor resident survival guide: Difference between revisions
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{{Family tree | F01 | | F02 | | F03 | | F04 | | F05 | | F06 | |F01= '''Complications''' |F02= Tachyarrhythmia less than Dopamine (less β1 effect) |F03= Arrhythmia (more β1) |F04= *Coronary spasm<br>*Splanchnic vasoconstriction|F05= Reflex bradycardia <br> (no worsening of tachycardia) <br>(only α1) |F06= Hypotension (β2) }} | {{Family tree | F01 | | F02 | | F03 | | F04 | | F05 | | F06 | |F01= '''Complications''' |F02= Tachyarrhythmia less than Dopamine (less β1 effect) |F03= Arrhythmia (more β1) |F04= *Coronary spasm<br>*Splanchnic vasoconstriction|F05= Reflex bradycardia <br> (no worsening of tachycardia) <br>(only α1) |F06= Hypotension (β2) }} | ||
{{Family tree | | | | | |!| | | |!| | | |!| | | |!| | | |!| | |}} | {{Family tree | | | | | |!| | | |!| | | |!| | | |!| | | |!| | |}} | ||
{{Family tree | G01 | | G02 | | G03 | | G04 | | G05 | | G06 | |G01= '''Cautions''' |G02= Arrhythmia |G03= *Not in cardiogenic shock <br>*Arrhythmia <br> *cardiotoxicity | {{Family tree | G01 | | G02 | | G03 | | G04 | | G05 | | G06 | |G01= '''Cautions''' |G02= Arrhythmia |G03= *'''Not in cardiogenic shock''' <br>*Arrhythmia <br> *Ischemia induced cardiotoxicity|G04= *Ischemic heart <br> *Gut ischemia |G05= *Bradycardia <br> *Heart block |G06= *Hypotension (add α1 agonist) }} | ||
{{Family tree/end}} | {{Family tree/end}} | ||
Revision as of 16:22, 6 December 2013
Sepsis Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
Definition
Causes
Life Threatening Causes
Common Causes
Prognosis
Management
Vasopressors | |||||||||||||||||||||||||||||||||||||||||||||||||
Norepinephrine | Dopamine | Vasopressin | Phenylephrine | Dobutamine | |||||||||||||||||||||||||||||||||||||||||||||
Mechanism | *Mainly predominantα1 agonist (Vasoconstrictive) *some β1 agonist (↑contractility) | *Mainly predominant β1 agonist (↑contractility) * some α1 agonist(Vasoconstrictive) | *V1 receptor of GIT vasculatures *Antidiuretic effects | *Pure α1 agonist(Vasoconstrictive) *No β1 | *Mainly predominant β1 agonist (↑contractility) *β2 arterial smooth muscle (Hypotensive) | ||||||||||||||||||||||||||||||||||||||||||||
Indication | *1st line in : *Septic shock *Cardiogenic shock *Undifferentiated shock | 2nd line septic shock | 2nd line septic shock | 1st line Neurogenic shock 3rd-4th line septic shock | *1st line cardiogenic shock * low output septic shock | ||||||||||||||||||||||||||||||||||||||||||||
Dose | 1-30 mcg/kg/min | 1-20 mcg/min | 0.03 unit/min | 20-300 mcg/kg/min | 2.5-20 mcg/kg/min | ||||||||||||||||||||||||||||||||||||||||||||
Complications | Tachyarrhythmia less than Dopamine (less β1 effect) | Arrhythmia (more β1) | *Coronary spasm *Splanchnic vasoconstriction | Reflex bradycardia (no worsening of tachycardia) (only α1) | Hypotension (β2) | ||||||||||||||||||||||||||||||||||||||||||||
Cautions | Arrhythmia | *Not in cardiogenic shock *Arrhythmia *Ischemia induced cardiotoxicity | *Ischemic heart *Gut ischemia | *Bradycardia *Heart block | *Hypotension (add α1 agonist) | ||||||||||||||||||||||||||||||||||||||||||||
Do's
- Assess the cause of shock
- Always volume fluid resuscitation first
- Norepinephrine in undifferentiated shock.