Acute liver failure resident survival guide: Difference between revisions
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Created page with "__NOTOC__ {{CMG}} {{AE}} {{VR}} ==Causes== ===Life Threatening Causes=== Life-threatening causes include conditions which may result in death or permanent disability within 2..." |
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==Do's== | ==Do's== | ||
==Dont's== | ==Dont's== | ||
==References== | ==References== | ||
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Revision as of 18:34, 6 December 2013
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Vendhan Ramanujam M.B.B.S [2]
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
Management
| Altered mental status and PT prolongation by 4-6 sec or INR ≥1.5 presenting w/ nonspecific abdominal Sx w/o preexisting chronic liver disease, cirrhosis and any illness of <26 wks duration | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Acute liver failure | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mandatory hospital admission | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| w/o altered mental status, significant coagulopathy and abnormal LFT | w/ altered mental status | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| High dependency ward admission | Worsening mental status | ICU admission | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Initial evaluation: Detailed H/o and PE Labs: CBC, PT/INR, serum BCH, ABG, ammonia, acetaminophen and tox screen for other drugs/toxins, viral serology (A-E), autoimmune markers, amylase, lipase, *bilirubin:alkaline phosphatase, blood grouping and typing, HIV status | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| General management | Etiology specific management | Complication specific management | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
General Management
Etiology Specific Management
Complication Specific Management
Do's
Dont's
References
| Continuous monitoring under quite environment w/ preventive treatment strategies | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cerebral edema and increased ICP | Coagulopathy | Drugs | GI bleeding | Hemodynamic instability | Hepatic encephalopathy | Infections | Metabolic disturbances | NAC | Nutritional deficiency | Renal failure | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||