Renal cell carcinoma classification: Difference between revisions
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| bgcolor="#ececec"|'''Papillary''' || 12|| MET <br> TFE3|| 13 %<br> < 1 % | | bgcolor="#ececec"|'''Papillary''' || 12|| MET <br> TFE3|| 13 %<br> < 1 % | ||
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| bgcolor="#ececec"|'''Chromophobe''' || 4 | | bgcolor="#ececec"|'''Chromophobe''' || 4 || || | ||
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| bgcolor="#ececec"|'''Oncocytoma''' || 4 | | bgcolor="#ececec"|'''Oncocytoma''' || 4 || || | ||
|- | |- | ||
|bgcolor="#ececec"|'''Collecting Duct''' || < 1 | |bgcolor="#ececec"|'''Collecting Duct''' || < 1 || || | ||
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|bgcolor="#ececec"|'''Unclassified''' || 3 - 5 | |bgcolor="#ececec"|'''Unclassified''' || 3 - 5 || || | ||
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<sup><center>Adapted from Cohen HT, McGovern FJ. Renal-cell carcinoma.''N Engl J Med''. 2005; 353:2477-90</center></sup> | <sup><center>Adapted from Cohen HT, McGovern FJ. Renal-cell carcinoma.''N Engl J Med''. 2005; 353:2477-90</center></sup> | ||
Revision as of 16:10, 27 December 2013
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Renal cell carcinoma Microchapters |
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Renal cell carcinoma classification On the Web |
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American Roentgen Ray Society Images of Renal cell carcinoma classification |
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Risk calculators and risk factors for Renal cell carcinoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
The following tables classify renal cell carcinoma according to histologic appearance and differentiates sporadic from hereditary forms of renal cell carcinoma.
| Histologic Appearance | Incidence | Gene | Frequency |
| Conventional | 75 | VHL | 60 % |
| Papillary | 12 | MET TFE3 |
13 % < 1 % |
| Chromophobe | 4 | ||
| Oncocytoma | 4 | ||
| Collecting Duct | < 1 | ||
| Unclassified | 3 - 5 |
| Syndrome | Associated Gene | Common Histological Appearance |
| VHL Disease | VHL | Conventional |
| FCRC | Chromosome 3p translocation | Conventional |
| Hereditary paraganglioma | SDHB | Conventional |
| HPRC | MET | Papillary |
| HLRCC | FH | Papillary |
| Birt-Hogg-Dube Syndrome | BHD | Chromophobe / Oncocytoma |
- Clear cell carcinoma (VHL and others on chromosome 3)
- Papillary carcinoma (MET, PRCC)
- Chromophobe renal carcinoma
- Collecting duct carcinoma
References
- ↑ 1.0 1.1 Cohen HT, McGovern FJ (2005). "Renal-cell carcinoma". N Engl J Med. 353 (23): 2477–90. doi:10.1056/NEJMra043172. PMID 16339096.