Penicillin G benzathine dosage and administration: Difference between revisions

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==Dosage and Administration==
==Dosage and Administration==


[[Streptococcus|Streptococcal (Group A) Upper Respiratory Infections]] (for example, pharyngitis)
*[[Streptococcus|Streptococcal (Group A) Upper Respiratory Infections]] (for example, pharyngitis)


Adults—a single injection of 1,200,000 units; older pediatric patients—a single injection of 900,000 units; infants and pediatric patients under 60 lbs.—300,000 to 600,000 units.
Adults—a single injection of 1,200,000 units; older pediatric patients—a single injection of 900,000 units; infants and pediatric patients under 60 lbs.—300,000 to 600,000 units.


[[Syphilis]]
*[[Syphilis]]


Primary, secondary, and latent—2,400,000 units (1 dose). Late (tertiary and neurosyphilis)—2,400,000 units at 7-day intervals for three doses.
Primary, secondary, and latent—2,400,000 units (1 dose). Late (tertiary and neurosyphilis)—2,400,000 units at 7-day intervals for three doses.
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Congenital—under 2 years of age: 50,000 units/kg/body weight; ages 2 to 12 years: adjust dosage based on adult dosage schedule.
Congenital—under 2 years of age: 50,000 units/kg/body weight; ages 2 to 12 years: adjust dosage based on adult dosage schedule.


Yaws, Bejel, and Pinta—1,200,000 units (1 injection).
*[[Yaws]], [[Bejel]], and [[Pinta]]—1,200,000 units (1 injection).


Prophylaxis—for rheumatic fever and glomerulonephritis.
*Prophylaxis—for rheumatic fever and glomerulonephritis.


Following an acute attack, penicillin G benzathine (parenteral) may be given in doses of 1,200,000 units once a month or 600,000 units every 2 weeks.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = BICILLIN L-A (PENICILLIN G BENZATHINE) INJECTION, SUSPENSION [A-S MEDICATION SOLUTIONS LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=77246068-b0b1-4267-9248-72000fa9de3e | publisher =  | date =  | accessdate}}</ref>
Following an acute attack, penicillin G benzathine (parenteral) may be given in doses of 1,200,000 units once a month or 600,000 units every 2 weeks.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = BICILLIN L-A (PENICILLIN G BENZATHINE) INJECTION, SUSPENSION [A-S MEDICATION SOLUTIONS LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=77246068-b0b1-4267-9248-72000fa9de3e | publisher =  | date =  | accessdate}}</ref>

Revision as of 18:46, 30 December 2013

Penicillin G benzathine
BICILLIN L-A® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Dosage and Administration

Adults—a single injection of 1,200,000 units; older pediatric patients—a single injection of 900,000 units; infants and pediatric patients under 60 lbs.—300,000 to 600,000 units.

Primary, secondary, and latent—2,400,000 units (1 dose). Late (tertiary and neurosyphilis)—2,400,000 units at 7-day intervals for three doses.

Congenital—under 2 years of age: 50,000 units/kg/body weight; ages 2 to 12 years: adjust dosage based on adult dosage schedule.

  • Prophylaxis—for rheumatic fever and glomerulonephritis.

Following an acute attack, penicillin G benzathine (parenteral) may be given in doses of 1,200,000 units once a month or 600,000 units every 2 weeks.[1]

References

  1. "BICILLIN L-A (PENICILLIN G BENZATHINE) INJECTION, SUSPENSION [A-S MEDICATION SOLUTIONS LLC]". Text " accessdate" ignored (help)

Adapted from the FDA Package Insert.