Cefprozil

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Synonyms: Cefprozilo [INN-Spanish], Cefprozil anhydrous, Cefprozilum [INN-Latin].

Brand Names: Arzimol, Brisoral, Cronocef, Procef, Serozil.

Dosing and Administration

Cefprozil tablets are administered orally.

Adults (13 years and older)

• Pharyngitis/Tonsillitis: 500 mg every 24h for 10 days.
• Acute sinusitis: 250 mg or 500 mg every 12h for 10 days.
• Secondary bacterial infection of acute bronchitis and acute bacterial exacerbation of chronic bronchitis: 500 mg every 12h for 10 days.
• Uncomplicated skin and skin structure infections: 250 mg every 12h for 10 days, 500 mg every 24h for 10 days, or 500 mg every 12h for 10 days.

Children (2 years-12 years)

• Pharyngitis/Tonsillitis: 7.5 mg/kg every 12h for 10 days.
• Uncomplicated skin and skin structure infections: 20 mg/kg every 24h for 10 days.

Infants & children (6 months-12 years)

• Otitis media: 15 mg/kg every 12h 10 days.
• Acute sinusitis: 7.5 mg/kg every 12h or 15 mg/kg every 12h for 10 days.

Renal impairment

• For patients with a creatinine clearance of 0-29 mL/min, administer 50% of the standard dosage in mg.

Hepatic impairment

• No dosage adjustment is necessary for patients with impaired hepatic function.

Adapted from the FDA Package Insert.