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<small>'''''Synonyms / Brand Names: Cefalessina, Cefalexin Sodium, Cefalexina, Cefalexine, Cefalexinum, Cephalexin 1-hydrate, Cephalexin hydrate, Cephalexin monohydrate, Cephalexinum, Cephalexine, CEX,Alcephin, Alexin, Alsporin, Biocef, Carnosporin, Cefa-iskia, Cefablan, Cefadal, Cefadin, Cefadina, Cefaleksin, Cefalin, Cefaloto, Cefaseptin, Cefax, Ceforal, Cefovit, Celexin, Cepastar, Cepexin, Cephacillin, Cephanasten, Cephaxin, Cephin, Cepol, Ceporex, Ceporex Forte, Ceporexin, Ceporexin-E, Ceporexine, Check, Cophalexin, Durantel, Durantel DS, Ed A-Ceph, Erocetin, Factagard, Felexin, Fexin, Ibilex, Ibrexin, Inphalex, Kefalospes, Keflet, Keflex, Kefolan, Keforal, Keftab, Kekrinal, Kidolex, L-Keflex, Lafarine, Larixin, Lenocef, Lexibiotico, Lonflex, Lopilexin, Madlexin, Mamalexin, Mamlexin, Medoxine, Neokef, Neolexina, Novolexin, Nufex, Oracef, Oriphex, Oroxin, Ortisporina, Ospexin, Palitrex, Panixine Disperdose, Pectril, Pyassan, Roceph, Sanaxin, Sartosona, Sencephalin, Sepexin, Servispor, Sialexin, Sinthecillin, Sporicef, Sporidex, Syncl, Syncle, Synecl, Tepaxin, Tokiolexin, Uphalexin, Voxxim, Winlex, Zozarine
__NOTOC__
''''' </small>
{{Cephalexin}}
{{CMG}};{{AE}}{{AK}}


{{CMG}}
==Overview==
Cephalexin (INN) or more commonly cephalexin /ˌsɛfəˈlɛksɨn/ is a first-generation cephalosporin antibiotic introduced in 1967 by Eli Lilly and Company.[2][3] It is an orally administered agent with a similar antimicrobial spectrum to the intravenous agents [[cefalotin]] and [[cefazolin]]. It was first marketed as Keflex (Lilly), and is marketed under several other trade names.


==Dosing and Administration==
==Category==
'''Adults'''<br>
Cephalosporins, first generation.
The adult dosage ranges from 1 to 4 g daily in divided doses. The usual adult dose is 250 mg every 6 hours. For the following infections, a dosage of 500 mg may be administered every 12 hours: streptococcal pharyngitis, skin and skin structure infections, and uncomplicated cystitis in patients over 15 years of age. Cystitis therapy should be continued for 7 to 14 days. For more severe infections or those caused by less susceptible organisms, larger doses may be needed. If daily doses of Keflex greater than 4 g are required, parenteral cephalosporins, in appropriate doses, should be considered.
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'''Pediatric Patients''' <br>
The usual recommended daily dosage for pediatric patients is 25 to 50 mg/kg in divided doses. For streptococcal pharyngitis in patients over 1 year of age and for skin and skin structure infections, the total daily dose may be divided and administered every 12 hours.
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''For more information on dosing please refer to'' [[Cephalexin instructions for administration|Instructions for administration]]
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[[{{PAGENAME}}#FDA Package Insert Resources|FDA Package Insert Resources]]
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[http://www.pace-med-apps.com/gfrcalc.htm Calculate Creatine Clearance]
<br></font size><small>On line calculator of your patients Cr Cl by a variety of formulas.</small><font size="4"><br>
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[http://home.earthlink.net/~sensei11/convert.htm Convert pounds to Kilograms]
<br></font size><small>On line calculator of your patients weight in pounds to Kg for dosing estimates.</small><font size="4"><br>
<br> [[{{PAGENAME}}#Publication Resources|Publication Resources]]
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[[{{PAGENAME}}#Trial Resources|Trial Resources]]
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[[{{PAGENAME}}#Media Resources|Media Resources]]
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[[{{PAGENAME}}#Patient Resources|Patient Resources]]
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[[{{PAGENAME}}#International Resources|International Resources]]
<br></font size><small>en Español</small><font size="4"><br>
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==FDA Package Insert Resources==
==US Brand Names==
[[{{PAGENAME}} indications|Indications]]
CEPHALEXIN<sup>®</sup>,KEFLEX<sup>®</sup>
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[[{{PAGENAME}} contraindications|Contraindications]]
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[[{{PAGENAME}} side effects|Side Effects]]
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[[{{PAGENAME}} drug interactions|Drug Interactions]]
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[[{{PAGENAME}} precautions|Precautions]]
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[[{{PAGENAME}} overdose|Overdose]]
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[[{{PAGENAME}} instructions for administration|Instructions for Administration]]
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[[{{PAGENAME}} how supplied|How Supplied]]
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[http://google2.fda.gov/search?q=cache:PNdbxe478sYJ:www.fda.gov/medwatch/SAFETY/2004/nov_PI/Keflex_PI.doc+Cephalexin&access=p&output=xml_no_dtd&ie=UTF-8&lr=&client=FDA&proxystylesheet=FDA&oe=UTF-8 FDA label]
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[http://google2.fda.gov/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&x=0&y=0&client=FDA&site=FDA&lr=&proxystylesheet=FDA&output=xml_no_dtd&getfields=* FDA on {{PAGENAME}}]
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</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
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==Publication Resources==
==Dosing and Administration==
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} Most Recent Articles on {{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}]
Cephalexin tablets, capsules and oral suspension are administered orally.
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[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}%20AND%20systematic%5Bsb%5D  Review Articles on {{PAGENAME}}]
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+AND+%28%28N+Engl+J+Med%5Bta%5D%29+OR+%28Lancet%5Bta%5D%29+OR+%28BMJ%5Bta%5D%29%29 Articles on {{PAGENAME}} in N Eng J Med, Lancet, BMJ]
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[[WikiDoc state of the art review on {{PAGENAME}}|WikiDoc State of the Art Review]]
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[http://books.google.com/books?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search&sa=N&tab=gp Textbook Information on {{PAGENAME}}]
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==Trial Resources==
[http://clinicaltrials.gov/search/open/condition={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} Ongoing Trials with {{PAGENAME}} at Clinical Trials.gov]
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+AND+%28randomized+controlled+trial%5BPublication+Type%5D+OR+%28randomized%5BTitle%2FAbstract%5D+AND+controlled%5BTitle%2FAbstract%5D+AND+trial%5BTitle%2FAbstract%5D%29%29 Trial Results with {{PAGENAME}}]
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==Guidelines & Evidence Based Medicine Resources==
==FDA Package Insert==
[http://www.guideline.gov/search/searchresults.aspx?Type=3&txtSearch={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&num=20 US National Guidelines Clearinghouse on {{PAGENAME}}]
'''  [[Cephalexin description|Description]]'''
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'''| [[Cephalexin clinical pharmacology|Clinical Pharmacology]]'''
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'''| [[Cephalexin microbiology|Microbiology]]'''
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:({{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}) AND (Cochrane Database Syst Rev[ta])}} Cochrane Collaboration on {{PAGENAME}}]
'''| [[Cephalexin indications and usage|Indications and Usage]]'''
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'''| [[Cephalexin contraindications|Contraindications]]'''
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'''| [[Cephalexin warnings and precautions|Warnings and Precautions]]'''
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:({{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}) AND (Cost effectiveness)}} Cost Effectiveness of {{PAGENAME}}]
'''| [[Cephalexin adverse reactions|Adverse Reactions]]'''
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'''| [[Cephalexin overdosage|Overdosage]]'''
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'''| [[Cephalexin clinical studies|Clinical Studies]]'''
</font size><small>[[{{PAGENAME}}#Dosing and Administration|Return to top]]</small><font size="4">
'''| [[Cephalexin dosage and administration|Dosage and Administration]]'''
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'''| [[Cephalexin how supplied|How Supplied]]'''
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'''| [[Cephalexin labels and packages|Labels and Packages]]'''
==Media Resources==
[http://www.google.com/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+ppt&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a Powerpoint Slides on {{PAGENAME}}]
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[http://images.google.com/images?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wi Images of {{PAGENAME}}]
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[http://www.google.com/search?hl=en&client=firefox-a&rls=org.mozilla%3Aen-US%3Aofficial&hs=hPo&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+podcasts+OR+MP3&btnG=Search Podcasts & MP3s on {{PAGENAME}}]
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[http://video.google.com/videosearch?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&um=1&sa=N&tab=fv# Videos on {{PAGENAME}}]
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==Patient Resources==
[[{{PAGENAME}} (patient information)|Patient Information from National Library of Medicine]]
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[http://www.google.com/search?hl=en&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+more:for_patients&cx=disease_for_patients&sa=N&oi=cooptsr&resnum=0&ct=col3&cd=1  Patient Resources on {{PAGENAME}}]
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[http://groups.google.com/groups/search?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search Discussion Groups on {{PAGENAME}}]
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[http://www.google.com/search?hl=en&client=firefox-a&rls=org.mozilla:en-US:official&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+more:patient_handouts&cx=disease_for_health_professionals&sa=N&oi=coopctx&resnum=0&ct=col1&cd=3 Patient Handouts on {{PAGENAME}}]
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[http://blogsearch.google.com/blogsearch?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wb Blogs on {{PAGENAME}}]
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[http://news.google.com/news?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wn {{PAGENAME}} in the News]
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[http://finance.google.com/finance?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search&sa=N&tab=te {{PAGENAME}} in the Marketplace]
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==International Resources==
[http://www.google.com/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+en+espanol&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a {{PAGENAME}} en Español]
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{{FDA}}


[[Category:Drugs]]
==References==
{{Reflist|2}}
http://www.accessdata.fda.gov/drugsatfda_docs/label/2006/050405s097lbl.pdf
[[Category:Antibiotics]]
[[Category:Wikinfect]]

Revision as of 15:01, 2 January 2014

Cephalexin
CEPHALEXIN®,KEFLEX® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]

Overview

Cephalexin (INN) or more commonly cephalexin /ˌsɛfəˈlɛksɨn/ is a first-generation cephalosporin antibiotic introduced in 1967 by Eli Lilly and Company.[2][3] It is an orally administered agent with a similar antimicrobial spectrum to the intravenous agents cefalotin and cefazolin. It was first marketed as Keflex (Lilly), and is marketed under several other trade names.

Category

Cephalosporins, first generation.

US Brand Names

CEPHALEXIN®,KEFLEX®

Dosing and Administration

Cephalexin tablets, capsules and oral suspension are administered orally.

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Clinical Studies | Dosage and Administration | How Supplied | Labels and Packages


References

http://www.accessdata.fda.gov/drugsatfda_docs/label/2006/050405s097lbl.pdf

Retrieved from "https://www.wikidoc.org/index.php?title=Cephalexin&oldid=922931"