Flucytosine drug interactions: Difference between revisions
Jump to navigation
Jump to search
Ahmed Zaghw (talk | contribs) (Created page with "__NOTOC__ {{Flucytosine}} {{CMG}}; {{AE}} {{AZ}} <ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = ANCOBON (FLUCYTOSINE) CAPSULE [VALEANT PHARMACEU...") |
Ahmed Zaghw (talk | contribs) No edit summary |
||
| Line 3: | Line 3: | ||
{{CMG}}; {{AE}} {{AZ}} | {{CMG}}; {{AE}} {{AZ}} | ||
==Drug Interactions== | |||
<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = ANCOBON (FLUCYTOSINE) CAPSULE [VALEANT PHARMACEUTICALS NORTH AMERICA LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=aea0df00-a88c-4a16-abcf-750f3ff2004e | publisher = | date = | accessdate = }}</ref> | Cytosine arabinoside, a cytostatic agent, has been reported to inactivate the antifungal activity of Ancobon by competitive inhibition. Drugs which impair glomerular filtration may prolong the biological half-life of flucytosine. | ||
===Drug/Laboratory Test Interactions=== | |||
Measurement of serum creatinine levels should be determined by the Jaffé reaction, since Ancobon does not interfere with the determination of creatinine values by this method. Most automated equipment for measurement of creatinine makes use of the Jaffé reaction.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = ANCOBON (FLUCYTOSINE) CAPSULE [VALEANT PHARMACEUTICALS NORTH AMERICA LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=aea0df00-a88c-4a16-abcf-750f3ff2004e | publisher = | date = | accessdate = }}</ref> | |||
==References== | ==References== | ||
Revision as of 19:36, 5 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
Drug Interactions
Cytosine arabinoside, a cytostatic agent, has been reported to inactivate the antifungal activity of Ancobon by competitive inhibition. Drugs which impair glomerular filtration may prolong the biological half-life of flucytosine.
Drug/Laboratory Test Interactions
Measurement of serum creatinine levels should be determined by the Jaffé reaction, since Ancobon does not interfere with the determination of creatinine values by this method. Most automated equipment for measurement of creatinine makes use of the Jaffé reaction.[1]
References
Adapted from the FDA Package Insert.