Flucytosine dosage and administration: Difference between revisions

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==Dosage and Administration==


<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = ANCOBON (FLUCYTOSINE) CAPSULE [VALEANT PHARMACEUTICALS NORTH AMERICA LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=aea0df00-a88c-4a16-abcf-750f3ff2004e | publisher =  | date =  | accessdate =  }}</ref>
The usual dosage of Ancobon is 50 to 150 mg/kg/day administered in divided doses at 6-hour intervals. Nausea or vomiting may be reduced or avoided if the capsules are given a few at a time over a 15-minute period. If the BUN or the serum creatinine is elevated, or if there are other signs of renal impairment, the initial dose should be at the lower level.
 
Ancobon should be used in combination with amphotericin B for the treatment of systemic candidiasis and cryptococcosis because of the emergence of resistance to Ancobon.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = ANCOBON (FLUCYTOSINE) CAPSULE [VALEANT PHARMACEUTICALS NORTH AMERICA LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=aea0df00-a88c-4a16-abcf-750f3ff2004e | publisher =  | date =  | accessdate =  }}</ref>


==References==
==References==

Latest revision as of 19:43, 5 January 2014

Flucytosine
ANCOBON® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]

Dosage and Administration

The usual dosage of Ancobon is 50 to 150 mg/kg/day administered in divided doses at 6-hour intervals. Nausea or vomiting may be reduced or avoided if the capsules are given a few at a time over a 15-minute period. If the BUN or the serum creatinine is elevated, or if there are other signs of renal impairment, the initial dose should be at the lower level.

Ancobon should be used in combination with amphotericin B for the treatment of systemic candidiasis and cryptococcosis because of the emergence of resistance to Ancobon.[1]

References

  1. "ANCOBON (FLUCYTOSINE) CAPSULE [VALEANT PHARMACEUTICALS NORTH AMERICA LLC]".

Adapted from the FDA Package Insert.