Interferon alfa-2a contraindications: Difference between revisions

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*Hypersensitivity to Roferon-A or any of its components
*Hypersensitivity to Roferon-A or any of its components
*Autoimmune hepatitis
*Autoimmune [[hepatitis]]
*Hepatic decompensation (Child-Pugh class B and C) before or during treatment
*Hepatic decompensation (Child-Pugh class B and C) before or during treatment



Revision as of 22:50, 5 January 2014

Interferon alfa-2a
PEGASYS® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Clinical Studies
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Contraindications

Roferon-A is contraindicated in patients with:

  • Hypersensitivity to Roferon-A or any of its components
  • Autoimmune hepatitis
  • Hepatic decompensation (Child-Pugh class B and C) before or during treatment

Roferon-A is contraindicated in neonates and infants because it contains benzyl alcohol. Benzyl alcohol is associated with an increased incidence of neurologic and other complications in neonates and infants, which are sometimes fatal.[1]

References

  1. "http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/103964s5204lbl.pdf" (PDF). External link in |title= (help)

Adapted from the FDA Package Insert.