Ticarcillin clavulanate: Difference between revisions
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{{Ticarcillin | {{Ticarcillin clavulanate}} | ||
{{CMG}}; {{AE}} {{MM}} | {{CMG}}; {{AE}} {{MM}} | ||
==Overview= | |||
==Overview= | |||
Ticarcillin is a [[carboxypenicillin]]. It is almost invariably sold and used in combination with clavulanate as '''Ticarcillin/clavulanic acid-TIMENTIN'''. Because it is a penicillin, it also falls within the larger class of [[beta-lactam]] antibiotics. Its main clinical use is as an injectable antibiotic for the treatment of [[gram-negative]]bacteria, particularly ''[[Pseudomonas aeruginosa]]''. It is also one of the few antibiotics capable of treating [[Stenotrophomonas maltophilia]] infections. | |||
==Category== | ==Category== | ||
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==FDA Package Insert== | ==FDA Package Insert== | ||
'''[[Ticarcillin | |||
'''| [[Ticarcillin | '''[[Ticarcillin clavulanate description|Description]]''' | ||
'''| [[Ticarcillin | '''| [[Ticarcillin clavulanate clinical pharmacology|Clinical Pharmacology]]''' | ||
'''| [[Ticarcillin | '''| [[Ticarcillin clavulanate microbiology|Microbiology]]''' | ||
'''| [[Ticarcillin | '''| [[Ticarcillin clavulanate indications and usage|Indications and Usage]]''' | ||
'''| [[Ticarcillin | '''| [[Ticarcillin clavulanate contraindications|Contraindications]]''' | ||
'''| [[Ticarcillin | '''| [[Ticarcillin clavulanate warnings and precautions|Warnings and Precautions]]''' | ||
'''| [[Ticarcillin | '''| [[Ticarcillin clavulanate adverse reactions|Adverse Reactions]]''' | ||
'''| [[Ticarcillin | '''| [[Ticarcillin clavulanate drug interactions|Drug Interactions]]''' | ||
'''| [[Ticarcillin | '''| [[Ticarcillin clavulanate overdosage|Overdosage]]''' | ||
'''| [[Ticarcillin | '''| [[Ticarcillin clavulanate dosage and administration|Dosage and Administration]]''' | ||
'''| [[Ticarcillin clavulanate how supplied|How Supplied]]''' | |||
==Mechanism of Action== | ==Mechanism of Action== | ||
Ticarcillin disrupts bacterial cell wall development by inhibiting peptidoglycan synthesis and/or by interacting with penicillin‑binding proteins.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = TIMENTIN (TICARCILLIN | Ticarcillin disrupts bacterial cell wall development by inhibiting peptidoglycan synthesis and/or by interacting with penicillin‑binding proteins.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = TIMENTIN (TICARCILLIN clavulanate AND CLAVULANATE POTASSIUM) INJECTION, POWDER, FOR SOLUTION TIMENTIN (TICARCILLIN clavulanate AND CLAVULANATE POTASSIUM) INJECTION, SOLUTION [GLAXOSMITHKLINE LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=8ffe8c3f-9694-4029-fca3-1b19c5cc2f93#nlm34089-3 | publisher = |date = | accessdate}}</ref> | ||
==References== | ==References== | ||
Revision as of 15:07, 7 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
=Overview
Ticarcillin is a carboxypenicillin. It is almost invariably sold and used in combination with clavulanate as Ticarcillin/clavulanic acid-TIMENTIN. Because it is a penicillin, it also falls within the larger class of beta-lactam antibiotics. Its main clinical use is as an injectable antibiotic for the treatment of gram-negativebacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections.
Category
US Brand Names
TIMENTIN®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Dosage and Administration | How Supplied
Mechanism of Action
Ticarcillin disrupts bacterial cell wall development by inhibiting peptidoglycan synthesis and/or by interacting with penicillin‑binding proteins.[1]