Ticarcillin clavulanate: Difference between revisions
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==Overview= | ==Overview== | ||
Ticarcillin is a [[carboxypenicillin]]. It is almost invariably sold and used in combination with clavulanate as '''Ticarcillin/clavulanic acid-TIMENTIN'''. Because it is a penicillin, it also falls within the larger class of [[beta-lactam]] antibiotics. Its main clinical use is as an injectable antibiotic for the treatment of [[gram-negative]]bacteria, particularly ''[[Pseudomonas aeruginosa]]''. It is also one of the few antibiotics capable of treating [[Stenotrophomonas maltophilia]] infections. | Ticarcillin is a [[carboxypenicillin]]. It is almost invariably sold and used in combination with clavulanate as '''Ticarcillin/clavulanic acid-TIMENTIN'''. Because it is a penicillin, it also falls within the larger class of [[beta-lactam]] antibiotics. Its main clinical use is as an injectable antibiotic for the treatment of [[gram-negative]]bacteria, particularly ''[[Pseudomonas aeruginosa]]''. It is also one of the few antibiotics capable of treating [[Stenotrophomonas maltophilia]] infections. | ||
Revision as of 15:07, 7 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Ticarcillin is a carboxypenicillin. It is almost invariably sold and used in combination with clavulanate as Ticarcillin/clavulanic acid-TIMENTIN. Because it is a penicillin, it also falls within the larger class of beta-lactam antibiotics. Its main clinical use is as an injectable antibiotic for the treatment of gram-negativebacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections.
Category
US Brand Names
TIMENTIN®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Dosage and Administration | How Supplied
Mechanism of Action
Ticarcillin disrupts bacterial cell wall development by inhibiting peptidoglycan synthesis and/or by interacting with penicillin‑binding proteins.[1]