Kanamycin: Difference between revisions

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==Overview==
==Overview==


Kanamycin sulfate is an [[aminoglycoside]] [[antibiotic]], available in both oral and [[intravenous]] forms, and used to treat a wide variety of[[infection]]s. Kanamycin is isolated from ''Streptomyces kanamyceticus''.
Kanamycin sulfate is an [[aminoglycoside]] [[antibiotic]], available in both oral and [[intravenous]] forms, and used to treat a wide variety of [[infection]]s. Kanamycin is isolated from ''Streptomyces kanamyceticus''.


==Category==
==Category==

Revision as of 16:20, 7 January 2014

Kanamycin
KANAMYCIN® Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Kanamycin sulfate is an aminoglycoside antibiotic, available in both oral and intravenous forms, and used to treat a wide variety of infections. Kanamycin is isolated from Streptomyces kanamyceticus.

Category

Aminoglycoside

US Brand Names

KANAMYCIN® (DISCONTINUED), KANAMYCIN SULFATE® (DISCONTINUED), KANTREX® (DISCONTINUED), KLEBCIL® (DISCONTINUED)

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Dosage and Administration | How Supplied | Labels and Packages

Mechanism of Action

Kanamycin works by affecting the 30S ribosomal subunit and causing a frameshift mutation or it prevents the translation of RNA.

Because of over-usage of antibiotics many bacteria have developed a resistance against kanamycin, and, consequently, it is not used much anymore.

Use in Research

Genes encoding kanamycin resistance are commonly used as selectable markers in molecular biology.

References