Terbinafine description: Difference between revisions
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Terbinafine tablets, USP contain the synthetic allylamine antifungal compound terbinafine hydrochloride USP. | Terbinafine tablets, USP contain the synthetic allylamine antifungal compound terbinafine hydrochloride USP. | ||
Latest revision as of 23:50, 7 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
Description
Terbinafine tablets, USP contain the synthetic allylamine antifungal compound terbinafine hydrochloride USP.
Chemically, terbinafine hydrochloride is (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine hydrochloride. The molecular formula C21H26ClN with a molecular weight of 327.90, and the following structural formula:
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Terbinafine hydrochloride USP is a white to off-white fine crystalline powder. It is freely soluble in methanol and methylene chloride, soluble in ethanol, and slightly soluble in water.
Each tablet contains:
Active Ingredient: Terbinafine hydrochloride USP (equivalent to 250 mg of terbinafine)
Inactive Ingredients: Microcrystalline cellulose, sodium starch glycolate, colloidal silicon dioxide, hypromellose, and magnesium stearate.[1]
References
Adapted from the FDA Package Insert.